Proliferating active matter

O Hallatschek, SS Datta, K Drescher, J Dunkel… - Nature Reviews …, 2023 - nature.com
The fascinating patterns of collective motion created by autonomously driven particles have
fuelled active-matter research for over two decades. So far, theoretical active-matter …

Computational models for active matter

MR Shaebani, A Wysocki, RG Winkler… - Nature Reviews …, 2020 - nature.com
Active matter, which ranges from molecular motors to groups of animals, exists at different
length scales and timescales, and various computational models have been proposed to …

Physics of active jamming during collective cellular motion in a monolayer

S Garcia, E Hannezo, J Elgeti… - Proceedings of the …, 2015 - National Acad Sciences
Although collective cell motion plays an important role, for example during wound healing,
embryogenesis, or cancer progression, the fundamental rules governing this motion are still …

Interplay of cell dynamics and epithelial tension during morphogenesis of the Drosophila pupal wing

R Etournay, M Popović, M Merkel, A Nandi, C Blasse… - Elife, 2015 - elifesciences.org
How tissue shape emerges from the collective mechanical properties and behavior of
individual cells is not understood. We combine experiment and theory to study this problem …

Simulating tissue mechanics with agent-based models: concepts, perspectives and some novel results

P Van Liedekerke, MM Palm, N Jagiella… - Computational particle …, 2015 - Springer
In this paper we present an overview of agent-based models that are used to simulate
mechanical and physiological phenomena in cells and tissues, and we discuss underlying …

Physical models of collective cell motility: from cell to tissue

BA Camley, WJ Rappel - Journal of physics D: Applied physics, 2017 - iopscience.iop.org
In this article, we review physics-based models of collective cell motility. We discuss a range
of techniques at different scales, ranging from models that represent cells as simple self …

Alignment of cellular motility forces with tissue flow as a mechanism for efficient wound healing

M Basan, J Elgeti, E Hannezo… - Proceedings of the …, 2013 - National Acad Sciences
Recent experiments have shown that spreading epithelial sheets exhibit a long-range
coordination of motility forces that leads to a buildup of tension in the tissue, which may …

Stress clamp experiments on multicellular tumor spheroids

F Montel, M Delarue, J Elgeti, D Vignjevic, G Cappello… - Biophysical …, 2012 - cell.com
In this work, we present two different approaches to measure the effect of mechanical stress
on tissue growth and death. The first setup use osmotic pressure to deform a dialysis bag …

Survival of the fittest: essential roles of cell competition in development, aging, and cancer

MM Merino, R Levayer, E Moreno - Trends in cell biology, 2016 - cell.com
Multicellular organisms evolved to resolve conflicts between individual cells, protecting the
internal organization of the individual. This is illustrated by cell competition, a process that …

Mechanically driven growth of quasi-two-dimensional microbial colonies

FDC Farrell, O Hallatschek, D Marenduzzo, B Waclaw - Physical review letters, 2013 - APS
We study colonies of nonmotile, rod-shaped bacteria growing on solid substrates. In our
model, bacteria interact purely mechanically, by pushing each other away as they grow, and …