Past, present, and future of deep brain stimulation: hardware, software, imaging, physiology and novel approaches

J Frey, J Cagle, KA Johnson, JK Wong… - Frontiers in …, 2022 - frontiersin.org
Deep brain stimulation (DBS) has advanced treatment options for a variety of neurologic and
neuropsychiatric conditions. As the technology for DBS continues to progress, treatment …

Deep brain stimulation creates informational lesion through membrane depolarization in mouse hippocampus

E Lowet, K Kondabolu, S Zhou, RA Mount… - Nature …, 2022 - nature.com
Deep brain stimulation (DBS) is a promising neuromodulation therapy, but the
neurophysiological mechanisms of DBS remain unclear. In awake mice, we performed high …

Deep brain stimulation in Parkinson's disease: state of the art and future perspectives

C França, RB Carra, JM Diniz, RP Munhoz… - Arquivos de Neuro …, 2022 - SciELO Brasil
For more than 30 years, Deep Brain Stimulation (DBS) has been a therapeutic option for
Parkinson's disease (PD) treatment. However, this therapy is still underutilized mainly due to …

Alternative patterns of deep brain stimulation in neurologic and neuropsychiatric disorders

RA Najera, AK Mahavadi, AU Khan… - Frontiers in …, 2023 - frontiersin.org
Deep brain stimulation (DBS) is a widely used clinical therapy that modulates neuronal firing
in subcortical structures, eliciting downstream network effects. Its effectiveness is determined …

Advances in Deep Brain Stimulation: From Mechanisms to Applications

SS Sandoval-Pistorius, ML Hacker… - Journal of …, 2023 - Soc Neuroscience
Deep brain stimulation (DBS) is an effective therapy for various neurologic and
neuropsychiatric disorders, involving chronic implantation of electrodes into target brain …

Advances in Deep Brain Stimulation: From Mechanisms to Applications.

M Hacker, A Waters, J Wang, N Provenza… - The Journal of …, 2023 - escholarship.org
Deep brain stimulation (DBS) is an effective therapy for various neurologic and
neuropsychiatric disorders, involving chronic implantation of electrodes into target brain …

Freezing of gait: pharmacological and surgical options

G Gámez-Leyva, E Cubo - Current Opinion in Neurology, 2024 - journals.lww.com
FOG requires different treatment strategies. The inclusion of adequate detection and
prediction of FoG combined with double-blind, and statistically powered protocols are …

Pilot Study of Acute Behavioral Effects of Pallidal Burst Stimulation in Parkinson's Disease

S Kariv, JW Choi, K Mirpour, AM Gordon… - Movement …, 2024 - Wiley Online Library
Background Burst‐patterned pallidal deep brain stimulation (DBS) in an animal model of
Parkinson's disease (PD) yields significantly prolonged therapeutic benefit compared to …

[HTML][HTML] Double blind, nonrandomized crossover study of active recharge biphasic deep brain stimulation for primary dystonia

JK Wong, JMLJ Lopes, W Hu, A Wang, KLK Au… - Parkinsonism & Related …, 2023 - Elsevier
Background Deep brain stimulation (DBS) of the globus pallidus interna (GPi) is an effective
therapy for select patients with primary dystonia. DBS programming for dystonia is often …

[HTML][HTML] Technological developments in electric-based DBS

M Tonge - Deep Brain Stimulation, 2024 - Elsevier
Modern electric-based deep brain stimulation (DBS) surgery has been a groundbreaking
treatment modality since its first successful application in 1987. There have been many …