Intracerebral recordings from movement disorders patients undergoing deep brain
stimulation have allowed the identification of pathophysiological patterns in oscillatory …

Translational experimental approaches that help us better trace Parkinson's disease (PD)
pathophysiological mechanisms leading to new therapeutic targets are urgently needed. In …

Parkinson's disease (PD) is a degenerative disease that can cause motor, cognitive, and
behavioral disorders. The treatment strategies being developed are based on the typical …

Delta oscillations (0.5–4 Hz) are a robust feature of basal ganglia pathophysiology in
patients with Parkinson's disease (PD) in relationship to tremor, but their relationship to other …

Excessive oscillatory activity across basal ganglia (BG) nuclei in the β frequencies (12–30
Hz) is a hallmark of Parkinson's disease (PD). While the link between oscillations and …

Background: Necroptosis is a form of programmed cell death resulting in tissue inflammation
due to the release of intracellular contents. Its role and regulatory mechanism in the context …

Deciphering the physiological patterns of motor network connectivity is a prerequisite to
elucidate aberrant oscillatory transformations and elaborate robust translational models of …

This study aimed to investigate the association between beta oscillations and brain iron
deposition. Beta oscillations were filtered from the microelectrode recordings of local field …

I have an incredible number of incredible people to thank for their help making this
dissertation a reality. First, to my advisors. Aryn Gittis and Jon Rubin, who have been the …