Long noncoding RNA and epithelial mesenchymal transition in cancer

M Gugnoni, A Ciarrocchi - International journal of molecular sciences, 2019 - mdpi.com
Epithelial–mesenchymal transition (EMT) is a multistep process that allows epithelial cells to
acquire mesenchymal properties. Fundamental in the early stages of embryonic …

lncRNA PVT1: a novel oncogene in multiple cancers

R Li, X Wang, C Zhu, K Wang - Cellular & molecular biology letters, 2022 - Springer
Long noncoding RNAs are involved in epigenetic gene modification, including binding to the
chromatin rearrangement complex in pre-transcriptional regulation and to gene promoters in …

PVT1 promotes cancer progression via MicroRNAs

W Wang, R Zhou, Y Wu, Y Liu, W Su, W Xiong… - Frontiers in …, 2019 - frontiersin.org
Non-coding RNA (ncRNA) plays a regulatory role in a variety of cellular activities. And long
non-coding RNA (lncRNA) is one of the important kinds of ncRNA. Previous studies have …

Linear and circular PVT1 in hematological malignancies and immune response: two faces of the same coin

M Ghetti, I Vannini, CT Storlazzi, G Martinelli… - Molecular cancer, 2020 - Springer
Non coding RNAs (ncRNAs) have emerged as regulators of human carcinogenesis by
affecting the expression of key tumor suppressor genes and oncogenes. They are divided …

Role of non-coding RNA networks in leukemia progression, metastasis and drug resistance

AA Bhat, SN Younes, SS Raza, L Zarif, S Nisar… - Molecular cancer, 2020 - Springer
Early-stage detection of leukemia is a critical determinant for successful treatment of the
disease and can increase the survival rate of leukemia patients. The factors limiting the …

Long noncoding RNAs in acute myeloid leukemia: functional characterization and clinical relevance

M Gourvest, P Brousset, M Bousquet - Cancers, 2019 - mdpi.com
Acute Myeloid Leukemia (AML) is the most common form of leukemia in adults with an
incidence of 4.3 per 100,000 cases per year. Historically, the identification of genetic …

[HTML][HTML] Aberrant LncRNA expression in leukemia

J Gao, F Wang, P Wu, Y Chen, Y Jia - Journal of Cancer, 2020 - ncbi.nlm.nih.gov
Leukemia is a common malignant cancer of the hematopoietic system, whose pathogenesis
has not been fully elucidated. Long noncoding RNAs (lncRNAs) are transcripts longer than …

Diagnostic and therapeutic implications of long non-coding rnas in leukemia

V Gasic, T Karan-Djurasevic, D Pavlovic, B Zukic… - Life, 2022 - mdpi.com
Simple Summary Research on leukemia has often led to novel approaches in clinical
practice. Cytogenetical and molecular markers have been introduced in treatment protocols …

Distinct clinical and biological characteristics of acute myeloid leukemia with higher expression of long noncoding RNA KIAA0125

YH Wang, CC Lin, CL Hsu, SY Hung, CY Yao… - Annals of …, 2021 - Springer
Expression of long non-coding RNA KIAA0125 has been incorporated in various gene
expression signatures for prognostic prediction in acute myeloid leukemia (AML) patients …

Long noncoding RNAs have pivotal roles in chemoresistance of acute myeloid leukemia

M Izadirad, L Jafari, AR James, JP Unfried, ZX Wu… - Drug Discovery …, 2021 - Elsevier
Many patients with acute myeloid leukemia (AML) experience poor outcomes following
traditional high-dose chemotherapies and complete remission rates remain suboptimal …