Physiology, signaling, and pharmacology of galanin peptides and receptors: three decades of emerging diversity

R Lang, AL Gundlach, FE Holmes, SA Hobson… - Pharmacological …, 2015 - Elsevier
Galanin was first identified 30 years ago as a" classic neuropeptide," with actions primarily
as a modulator of neurotransmission in the brain and peripheral nervous system. Other …

Functions of galanin, spexin and kisspeptin in metabolism, mood and behaviour

EG Mills, C Izzi-Engbeaya, A Abbara… - Nature Reviews …, 2021 - nature.com
The bioactive peptides galanin, spexin and kisspeptin have a common ancestral origin and
their pathophysiological roles are increasingly the subject of investigation. Evidence …

Unravelling innervation of pancreatic islets

RF Hampton, M Jimenez-Gonzalez, SA Stanley - Diabetologia, 2022 - Springer
The central and peripheral nervous systems play critical roles in regulating pancreatic islet
function and glucose metabolism. Over the last century, in vitro and in vivo studies along …

Galanin receptors and ligands

KEB Webling, J Runesson, T Bartfai… - Frontiers in …, 2012 - frontiersin.org
The neuropeptide galanin was first discovered 30 years ago. Today, the galanin family
consists of galanin, galanin-like peptide (GALP), galanin-message associated peptide …

Neuropeptides in epilepsy

S Kovac, MC Walker - Neuropeptides, 2013 - Elsevier
Neuropeptides play an important role in modulating seizures and epilepsy. Unlike
neurotransmitters which operate on a millisecond time-scale, neuropeptides have longer …

The nutrient‐sensing repertoires of mouse enterochromaffin cells differ between duodenum and colon

AM Martin, AL Lumsden, RL Young… - …, 2017 - Wiley Online Library
Background Enterochromaffin (EC) cells within the gastrointestinal (GI) tract provide almost
all body serotonin (5‐hydroxytryptamine [5‐HT]). Peripheral 5‐HT, released from EC cells …

The role of spexin in energy metabolism

X Sun, Z Yu, Y Xu, S Pu, X Gao - Peptides, 2023 - Elsevier
Spexin, also identified as neuropeptide Q (NPQ), is a 14 amino acid peptide discovered by
bioinformatic methods. It has a conserved structure in many species and is widely expressed …

Neuropeptide receptors as potential drug targets in the treatment of inflammatory conditions

E Pintér, G Pozsgai, Z Hajna, Z Helyes… - British journal of …, 2014 - Wiley Online Library
Cross‐talk between the nervous, endocrine and immune systems exists via regulator
molecules, such as neuropeptides, hormones and cytokines. A number of neuropeptides …

How does cigarette smoking cause acute pancreatitis?

SG Barreto - Pancreatology, 2016 - Elsevier
Abstract Introduction Acute Pancreatitis (AP) is an emerging health problem world-wide and
it is a major cause of admissions for gastrointestinal disease in many countries. Amongst the …

Drug-induced acute pancreatitis in a cohort of 328 patients. A single-centre experience from Australia

SG Barreto, L Tiong, R Williams - JOP. Journal of the Pancreas, 2011 - serena.unina.it
Context Acute pancreatitis is associated with risk of morbidity and even mortality. Routine
prescription drugs have been linked to the causation of acute pancreatitis. Objective To …