Sonogashira coupling involves coupling of vinyl/aryl halides with terminal acetylenes
catalyzed by transition metals, especially palladium and copper. This is a well known …

Indazoles are a very important class of N‐containing heterocycles with a wide range of
biological and medicinal properties. The presence of different functionalities on indazole …

Covering the fundamentals of heterocyclic reactivity and synthesis, this book teaches the
subject in a way that is understandable to graduate students. Recognizing the level at which …

The specificities of 65 compounds reported to be relatively specific inhibitors of protein
kinases have been profiled against a panel of 70–80 protein kinases. On the basis of this …

Indazoles are of considerable interest due to the broad variety of their biological activities.
This overview summarizes structures of pharmacologically interesting indazoles published …

Abstract N-Methoxy-N-methylamide, popularly addressed as the Weinreb amide, has
surfaced as an amide with a difference. This amide has served as an excellent acylating …

Devising novel multicomponent reactions (MCRs) that achieve the formation of multiple
bonds in one operation is one of the major challenges in modern organic synthesis.[1] As …

Syntheses of 3-substituted indazoles and benzoisoxazoles were efficiently accomplished
with the aid of Pd-catalyzed intramolecular carbon–nitrogen and carbon–oxygen bond …

The specific targeting of oncogenic mutant epidermal growth factor receptor (EGFR) is a
breakthrough in targeted cancer therapy and marks a drastic change in the treatment of non …

A Pd-catalyzed cascade process for the direct synthesis of 3-substituted-1 H-indazole
employing p-quinone methide (p-QM) and arylhydrazine through Pd-catalyzed double C–N …