Mass spectrometry (MS) has become a central technique in cancer research. The ability to
analyze various types of biomolecules in complex biological matrices makes it well suited for …

Spatial metabolomics is an emerging field of omics research that has enabled localizing
metabolites, lipids, and drugs in tissue sections, a feat considered impossible just two …

Clear cell renal cell carcinoma (ccRCC) is a complex disease with remarkable immune and
metabolic heterogeneity. Here we perform genomic, transcriptomic, proteomic, metabolomic …

Specialized metabolite (SM) diversification is a core process to plants' adaptation to diverse
ecological niches. Here, we implemented a computational mass spectrometry–based …

High-spatial-resolution mass spectrometry imaging (HSR-MSI) provides precise spatial
information on thousands of biomolecules without labelling across a tissue section. Deep …

Glycosylation is an important posttranslational modifier of proteins and lipid conjugates
critical for the stability and function of these macromolecules. Particularly important are N …

New mass spectrometry imaging (MSI) techniques are gaining importance in various stages
of the drug discovery and development chain as well as in more fundamental studies of drug …

Molecular imaging has the potential to unearth important spatial and temporal relationships
in biological systems, including intercellular signaling as well as environmentally-cued …

Mass spectrometry imaging (MSI) has become a widespread analytical technique to perform
nonlabeled spatial molecular identification. The Achilles' heel of MSI is the annotation and …

Mass spectrometry imaging (MSI) techniques generate data that reveal spatial distributions
of molecules on a surface with high sensitivity and selectivity. However, processing large …