An excess of saturated fatty acids and simple sugars in the diet is a known environmental
risk factor of Alzheimer's disease (AD) but the holistic view of the interacting processes …

The Western diet (WD) pattern characterized by high daily intake of saturated fats and
refined carbohydrates often leads to obesity and overweight, and it has been linked to …

Obesity is defined as abnormal and excessive fat accumulation, and it is a risk factor for
developing metabolic and neurodegenerative diseases and cognitive deficits. Obesity is …

Obesity, type 2 diabetes, and their associated comorbidities impact brain metabolism and
function and constitute risk factors for cognitive impairment. Alterations to taurine …

Dietary proteins have been used for years to treat obesity. Body weight loss is beneficial
when it concerns fat mass, but loss of fat free mass–especially muscle might be detrimental …

High-fat diet (HFD) consumption leads to obesity and a chronic state of low-grade
inflammation, named metainflammation. Notably, metainflammation contributes to …

Impairment of insulin action and metabolic dysregulation have traditionally been associated
with schizophrenia, although the molecular basis of such association remains still elusive …

The metabolic dysfunctions induced by high fat diet (HFD) consumption are not limited to
organs involved in energy metabolism but cause also a chronic low-grade systemic …

Brain insulin resistance links the failure of energy metabolism with cognitive decline in both
type 2 Diabetes Mellitus (T2D) and Alzheimer's disease (AD), although the molecular …

Type 2 diabetes (T2D) is a metabolic disease with impact on brain function through
mechanisms that include glucose toxicity, vascular damage and blood–brain barrier (BBB) …