Simple Summary Microtubules (MTs) are dynamic structures that compose part of the cell
cytoskeleton. They play important roles in various cellular functions, such as intracellular …

Microtubules are polar cytoskeletal filaments assembled from head-to-tail and comprised of
lateral associations of α/β-tubulin heterodimers that play key role in various cellular …

Nervous system function and plasticity rely on the complex architecture of neuronal networks
elaborated during development, when neurons acquire their specific and complex shape …

How temperature specifically affects microtubule dynamics and how these lead to changes
in microtubule networks in cells have not been established. We investigated these questions …

Background The repressor element-1 silencing transcription factor/neuron-restrictive
silencer factor (REST/NRSF) is a master regulator of neuronal gene expression. REST …

Actins and tubulins are abundant cytoskeletal proteins that support diverse cellular
processes. Owing to the unique properties of these filament-forming proteins, an intricate …

Tubulin folding cofactors (TFCs) are required for tubulin folding, α/β tubulin heterodimer
formation, and microtubule (MT) dynamics in yeast and mammals. However, the functions of …

Intermediate filaments represent the most abundant cytoskeletal element in mature neurons.
Mutations and/or accumulations of neuronal intermediate filament proteins are frequently …

Genetic and functional studies suggest diverse pathways being affected in the
neurodegenerative disease amyotrophic lateral sclerosis (ALS), while knowledge about …

Primary microcephaly is a disorder of brain development characterized by a congenitally
small but normally formed brain, and non‐progressive mild‐to‐moderate mental retardation …