Cytokines in gingivitis and periodontitis: from pathogenesis to therapeutic targets

N Neurath, M Kesting - Frontiers in Immunology, 2024 - frontiersin.org
Chronic inflammatory processes in the oral mucosa and periodontitis are common disorders
caused by microflora and microbial biofilms. These factors activate both the innate and …

IL‐17: Balancing Protective Immunity and Pathogenesis

L Sun, L Wang, BB Moore, S Zhang… - Journal of …, 2023 - Wiley Online Library
The biological role of interleukin 17 (IL‐17) has been explored during recent decades and
identified as a pivotal player in coordinating innate and adaptive immune responses …

Casp11 Deficiency Alters Subgingival Microbiota and Attenuates Periodontitis

SL Fu, YY Qian, AN Dai, HY Li, XH Jin… - Journal of Dental …, 2024 - journals.sagepub.com
Periodontitis (PD) is the primary cause of tooth loss in adults. Porphyromonas gingivalis
(Pg), a keystone pathogen, has been identified as a crucial contributor to this process …

m6A methylation in myocardial tissue of septic mice analyzed using MeRIP/m6A-sequencing and RNA-sequencing

X Liang, X Hu, J Li, B Zhang, T Gu, H Wang… - Functional & Integrative …, 2024 - Springer
Septic cardiomyopathy is a secondary myocardial injury caused by sepsis. N6-methyl-
adenosine (m6A) modification is involved in the pathological progression of septic …

Type I Interferon Protects Against Bone Loss in Periodontitis by Mitigating an Interleukin (Il)-17-Neutrophil Axis

S Zhang, J Zhang, A Wang, M Lin, N Yu, K Moss… - Available at SSRN … - papers.ssrn.com
Abstract Type I interferons (IFNs-I), a group of pleiotropic cytokines, critically modulate host
response in various inflammatory diseases. However, the role of the IFN-I pathway in …