G protein-coupled receptor signaling pathways mediate the transmission of signals from the
extracellular environment to the generation of cellular responses, a process that is critically …

As negative modulators of G-protein-coupled receptors (GPCRs) signaling, regulators of G
protein signaling (RGS) proteins facilitate various downstream cellular signalings through …

The extent and temporal characteristics of G protein–coupled receptor (GPCR) signaling are
shaped by the regulator of G protein signaling (RGS) proteins, which promote G protein …

Regulators of G protein signaling (RGS) proteins modulate the physiologic actions of many
neurotransmitters, hormones, and other signaling molecules. Human RGS proteins …

Dopamine D2 receptor signaling is central for striatal function and movement, while
abnormal activity is associated with neurological disorders including the severe early‐onset …

Signaling via G-protein-coupled receptors (GPCRs) is central for the function of biological
systems. Many clinically used drugs target GPCRs directly or target molecules involved in …

Regulators of G-protein signaling (RGS) proteins enhance the intrinsic GTPase activity of G
protein α (Gα) subunits and are vital for proper signaling kinetics downstream of G protein …

As the molecular mechanisms of vertebrate phototransduction became increasingly clear in
the 1980s, a persistent problem was the discrepancy between the slow GTP hydrolysis …

Regulators of G protein signaling (RGS) are a family of proteins classically known to
accelerate the intrinsic GTPase activity of G proteins, which results in accelerated …

Regulators of G protein signalling (RGS) proteins are celebrating the 20th anniversary of
their discovery. The unveiling of this new family of negative regulators of G protein signalling …