Passive, active and endogenous organ-targeted lipid and polymer nanoparticles for delivery of genetic drugs
SA Dilliard, DJ Siegwart - Nature Reviews Materials, 2023 - nature.com
Genetic drugs based on nucleic acid biomolecules are a rapidly emerging class of
medicines that directly reprogramme the central dogma of biology to prevent and treat …
medicines that directly reprogramme the central dogma of biology to prevent and treat …
Circulating tumor cell isolation for cancer diagnosis and prognosis
Circulating tumor cells (CTCs) are tumor cells that shed from the primary tumor and
intravasate into the peripheral blood circulation system responsible for metastasis. Sensitive …
intravasate into the peripheral blood circulation system responsible for metastasis. Sensitive …
Protein nanoparticles in drug delivery: animal protein, plant proteins and protein cages, albumin nanoparticles
E Kianfar - Journal of Nanobiotechnology, 2021 - Springer
In this article, we will describe the properties of albumin and its biological functions, types of
sources that can be used to produce albumin nanoparticles, methods of producing albumin …
sources that can be used to produce albumin nanoparticles, methods of producing albumin …
The effects of protein corona on in vivo fate of nanocarriers
With the emerging advances in utilizing nanocarriers for biomedical applications, a
molecular-level understanding of the in vivo fate of nanocarriers is necessary. After …
molecular-level understanding of the in vivo fate of nanocarriers is necessary. After …
Concepts of nanoparticle cellular uptake, intracellular trafficking, and kinetics in nanomedicine
Nanoparticle-based therapeutics and diagnostics are commonly referred to as
nanomedicine and may significantly impact the future of healthcare. However, the clinical …
nanomedicine and may significantly impact the future of healthcare. However, the clinical …
Reactive oxygen species formed by metal and metal oxide nanoparticles in physiological media—a review of reactions of importance to nanotoxicity and proposal for …
Diffusely dispersed metal and metal oxide nanoparticles (NPs) can adversely affect living
organisms through various mechanisms and exposure routes. One mechanism behind their …
organisms through various mechanisms and exposure routes. One mechanism behind their …
DLS and zeta potential–what they are and what they are not?
S Bhattacharjee - Journal of controlled release, 2016 - Elsevier
Adequate characterization of NPs (nanoparticles) is of paramount importance to develop
well defined nanoformulations of therapeutic relevance. Determination of particle size and …
well defined nanoformulations of therapeutic relevance. Determination of particle size and …
Mesoporous bioactive glasses in cancer diagnosis and therapy: stimuli‐responsive, toxicity, immunogenicity, and clinical translation
Cancer is one of the top life‐threatening dangers to the human survival, accounting for over
10 million deaths per year. Bioactive glasses have developed dramatically since their …
10 million deaths per year. Bioactive glasses have developed dramatically since their …
Protein corona: a new approach for nanomedicine design
After administration of nanoparticle (NP) into biological fluids, an NP–protein complex is
formed, which represents the “true identity” of NP in our body. Hence, protein–NP interaction …
formed, which represents the “true identity” of NP in our body. Hence, protein–NP interaction …
'Passive'nanoparticles for organ-selective systemic delivery: design, mechanism and perspective
Nanotechnology has shown tremendous success in the drug delivery field for more effective
and safer therapy, and has recently enabled the clinical approval of RNA medicine, a new …
and safer therapy, and has recently enabled the clinical approval of RNA medicine, a new …