The development of immune-checkpoint inhibitors (ICIs) has heralded a new era in cancer
treatment, enabling the possibility of long-term survival in patients with metastatic disease …

With immune checkpoint inhibitors (ICIs) becoming the mainstay of treatment for many
cancers, managing their immune-related adverse events (irAEs) has become an important …

Highlights•This review collected the available evidence on the role of immunotherapy on
fertility, hypogonadism, and sexuality.•Immune checkpoint inhibitors could impair fertility.• …

The addition of immune checkpoint inhibitors (ICIs) to the therapeutic armamentarium for
solid malignancies has resulted in unprecedented improvements in patient outcomes in …

The human conceptus is a semi-allograft, which is antigenically foreign to the mother.
Hence, the implantation process needs mechanisms to prevent allograft rejection during …

Abstract Background Immune checkpoint inhibitors (ICIs) have become a central part of
cancer care. However, the survivorship outcomes in patients treated with ICIs are …

Background: Over the past decades, advancements in oncological treatments have led to
major improvements in survival. Particularly for adolescents and young adults (AYAs) …

Cutaneous melanoma, the most aggressive type of skin cancer, remains one the most
represented forms of cancer in the United States and European countries, representing, in …

Abstract Purpose of Review Although fertility preservation is not yet fully integrated into the
comprehensive cancer care of pediatric and adolescent patients, advances continue to take …

In recent years, the indications for immunotherapy in cancer treatment have been
expanding. The increased risk of cancer in young people, coupled with the fact that many …