Methylation of cytosine bases in DNA provides a layer of epigenetic control in many
eukaryotes that has important implications for normal biology and disease. Therefore …

Methylation of cytosines can mediate epigenetic gene silencing and is the only known DNA
modification in eukaryotes. Recent efforts to map DNA methylation across mammalian …

Recent expansion of our knowledge on epigenetic changes strongly suggests that not only
nuclear DNA (nDNA), but also mitochondrial DNA (mtDNA) may be subjected to epigenetic …

Several types of epigenetic marks facilitate the complex patterning required for normal
human development. These epigenetic marks include DNA methylation at CpG …

BACKGROUND & AIMS: Deregulation of forkhead box (Fox) proteins, an evolutionarily
conserved family of transcriptional regulators, leads to tumorigenesis. Little is known about …

DNA methylation, consisting of the addition of a methyl group at the fifth‐position of cytosine
in a CpG dinucleotide, is one of the most well‐studied epigenetic mechanisms in mammals …

DNA methylation is one of several epigenetic changes observed in cells. Aberrant
methylation of tumor suppressor genes, proto-oncogenes, and vital cell cycle genes has led …

The etiology of obesity is multifactorial, involving complex interactions among the genetic
makeup, neuroendocrine status, fetal programming, and different unhealthy environmental …

Epigenetics refers to nucleotide sequence-independent events, and heritable changes,
including DNA methylation and histone modification (as the two main processes) …

DNA methylation plays a critical role in the regulation of gene expression. The ability to
access the methylation status for a large number of genes or the entire genome should …