RUNX transcription factors: orchestrators of development
ABSTRACT RUNX transcription factors orchestrate many different aspects of biology,
including basic cellular and developmental processes, stem cell biology and tumorigenesis …
including basic cellular and developmental processes, stem cell biology and tumorigenesis …
RUNX family: Regulation and diversification of roles through interacting proteins
LSH Chuang, K Ito, Y Ito - International journal of cancer, 2013 - Wiley Online Library
The Runt‐related transcription factors (RUNX) belong to an ancient family of metazoan
genes involved in developmental processes. Through multiple protein‐interacting partners …
genes involved in developmental processes. Through multiple protein‐interacting partners …
Epstein–Barr virus reprograms human B lymphocytes immediately in the prelatent phase of infection
P Mrozek-Gorska, A Buschle, D Pich… - Proceedings of the …, 2019 - National Acad Sciences
Epstein–Barr virus (EBV) is a human tumor virus and a model of herpesviral latency. The
virus efficiently infects resting human B lymphocytes and induces their continuous …
virus efficiently infects resting human B lymphocytes and induces their continuous …
Epstein-Barr virus exploits intrinsic B-lymphocyte transcription programs to achieve immortal cell growth
Epstein-Barr virus nuclear antigen 2 (EBNA2) regulation of transcription through the cell
transcription factor RBPJ is essential for resting B-lymphocyte (RBL) conversion to immortal …
transcription factor RBPJ is essential for resting B-lymphocyte (RBL) conversion to immortal …
Specification of neuronal subtypes in the spiral ganglion begins prior to birth in the mouse
TR Sanders, MW Kelley - Proceedings of the National …, 2022 - National Acad Sciences
The afferent innervation of the cochlea is comprised of spiral ganglion neurons (SGNs),
which are characterized into four subtypes (Type 1A, B, and C and Type 2). However, little is …
which are characterized into four subtypes (Type 1A, B, and C and Type 2). However, little is …
RUNX3 is multifunctional in carcinogenesis of multiple solid tumors
LSH Chuang, Y Ito - Oncogene, 2010 - nature.com
The study of RUNX3 in tumor pathogenesis is a rapidly expanding area of cancer research.
Functional inactivation of RUNX3—through mutation, epigenetic silencing, or cytoplasmic …
Functional inactivation of RUNX3—through mutation, epigenetic silencing, or cytoplasmic …
The RUNX family in breast cancer: relationships with estrogen signaling
NO Chimge, B Frenkel - Oncogene, 2013 - nature.com
The three RUNX family members are lineage specific master regulators, which also have
important, context-dependent roles in carcinogenesis as either tumor suppressors or …
important, context-dependent roles in carcinogenesis as either tumor suppressors or …
Genome-wide association study implicates chromosome 9q21. 31 as a susceptibility locus for asthma in mexican children
DB Hancock, I Romieu, M Shi, JJ Sienra-Monge… - PLoS …, 2009 - journals.plos.org
Many candidate genes have been studied for asthma, but replication has varied. Novel
candidate genes have been identified for various complex diseases using genome-wide …
candidate genes have been identified for various complex diseases using genome-wide …
Fast and flexible joint fine-mapping of multiple traits via the Sum of Single Effects model
We introduce mvSuSiE, a multi-trait fine-mapping method for identifying putative causal
variants from genetic association data (individual-level or summary data). mvSuSiE learns …
variants from genetic association data (individual-level or summary data). mvSuSiE learns …
AB cell regulome links notch to downstream oncogenic pathways in small B cell lymphomas
Gain-of-function Notch mutations are recurrent in mature small B cell lymphomas such as
mantle cell lymphoma (MCL) and chronic lymphocytic leukemia (CLL), but the Notch target …
mantle cell lymphoma (MCL) and chronic lymphocytic leukemia (CLL), but the Notch target …