Objective To evaluate the trends and cross-country inequalities of global osteoarthritis (OA)
burden over the last 30 years, and further predicted its changes to 2035. Methods The …

Despite advances in the treatment of cancers through surgical procedures and new
pharmaceuticals, the treatment of hepatocellular carcinoma (HCC) remains challenging as …

Objective To estimate systematic and anatomic site–specific age‐standardized prevalence
rates (ASRs) and analyze the secular trends of osteoarthritis (OA) at global, regional, and …

Importance Preterm birth complications are the leading cause of death in children younger
than 5 years worldwide. Despite advancing knowledge of risk factors and mechanisms …

Background Obesity represents an urgent problem that needs to be properly addressed,
especially among children. Public and global health policy-and decision-makers need …

Objective Depression is the most common mental illness worldwide. It has become an
important public health problem. This study aimed to determine the global burden of …

Background and Objectives Ischemic stroke (IS), 1 of the 2 main subtypes of stroke, occurs
because of brain ischemia caused by thrombosis of a cerebral blood vessel. IS is one of the …

To provide comprehensive estimates of the global, regional, and national burden of infertility
from 1990 to 2017, using findings from a 2017 study on the global burden of disease (GBD) …

Aims The aim of this study was to estimate the burden and risk factors for ischaemic heart
disease (IHD) in 195 countries and territories from 1990 to 2017. Methods and results Data …

Intratumor heterogeneity may result from the evolution of tumor cells and their continuous
interactions with the tumor microenvironment which collectively drives tumorigenesis …