Circadian rhythms and pain

JR Bumgarner, WH Walker II, RJ Nelson - Neuroscience & Biobehavioral …, 2021 - Elsevier
The goal of this review is to provide a perspective on the nature and importance of the
relationship between the circadian and pain systems. We provide: 1) An overview of the …

Differential effects of constant light and dim light at night on the circadian control of metabolism and behavior

VS Rumanova, M Okuliarova, M Zeman - International Journal of …, 2020 - mdpi.com
The disruption of circadian rhythms by environmental conditions can induce alterations in
body homeostasis, from behavior to metabolism. The light: dark cycle is the most reliable …

[HTML][HTML] Mechanisms and pathways of pain photobiomodulation: a narrative review

K Cheng, LF Martin, MJ Slepian, AM Patwardhan… - The journal of pain, 2021 - Elsevier
A growing body of evidence supports the modulation of pain by light exposure. As such,
phototherapy is being increasingly utilized for the management of a variety of pain …

Light at night disrupts biological clocks, calendars, and immune function

WH Walker, JR Bumgarner, DD Becker-Krail… - Seminars in …, 2022 - Springer
Light at night is a pervasive problem in our society; over 80% of the world's population
experiences significant light pollution. Exacerbating this issue is the reality that artificially lit …

Circadian disruption and consequences on innate immunity and inflammatory response

V Jerigova, M Zeman, M Okuliarova - International Journal of Molecular …, 2022 - mdpi.com
Circadian rhythms control almost all aspects of physiology and behavior, allowing temporal
synchrony of these processes between each other, as well as with the external environment …

[HTML][HTML] Aging, circadian disruption and neurodegeneration: Interesting interplay

AK Verma, S Singh, SI Rizvi - Experimental Gerontology, 2023 - Elsevier
The circadian system is an intricate molecular network of coordinating circadian clocks that
organize the internal synchrony of the organism in response to the environment. These …

Dim light at night induced neurodegeneration and ameliorative effect of curcumin

D Namgyal, K Chandan, A Sultan, M Aftab, S Ali… - Cells, 2020 - mdpi.com
It is a well-known fact that following a proper routine light/dark or diurnal rhythm controls
almost all biological processes. With the introduction of modern lighting and artificial …

The disruptive relationship among circadian rhythms, pain, and opioids

JR Bumgarner, EW McCray, RJ Nelson - Frontiers in Neuroscience, 2023 - frontiersin.org
Pain behavior and the systems that mediate opioid analgesia and opioid reward processing
display circadian rhythms. Moreover, the pain system and opioid processing systems …

Dim light at night shifts microglia to a pro-inflammatory state after cerebral ischemia, altering stroke outcome in mice

JA Liu, WH Walker II, OH Meléndez-Fernández… - Experimental …, 2024 - Elsevier
Circadian rhythms are endogenous biological cycles that regulate physiology and behavior
and are set to precisely 24-h by light exposure. Light at night (LAN) dysregulates physiology …

Dim artificial light at night alters immediate early gene expression throughout the avian brain

CK Hui, N Chen, A Chakraborty, V Alaasam… - Frontiers in …, 2023 - frontiersin.org
Artificial light at night (ALAN) is a pervasive pollutant that alters physiology and behavior.
However, the underlying mechanisms triggering these alterations are unknown, as previous …