Catalytic functionalization of indoles in a new dimension

M Bandini, A Eichholzer - Angewandte Chemie International …, 2009 - Wiley Online Library
Abstract 140 Years ago Adolf von Baeyer proposed the structure of a heteroaromatic
compound which revolutionized organic and medical chemistry: indole. After more than a …

Synthetic approaches to 3-(2-nitroalkyl) indoles and their use to access tryptamines and related bioactive compounds

S Lancianesi, A Palmieri, M Petrini - Chemical Reviews, 2014 - ACS Publications
The assembly of architecturally complex alkaloids embedding the indole nucleus is of
paramount importance for the target oriented synthesis of biologically active molecules. 1 A …

Katalytische Funktionalisierung von Indolen in einer neuen Dimension

M Bandini, A Eichholzer - Angewandte Chemie, 2009 - Wiley Online Library
Abstract Vor 140 Jahren schlug Adolf von Baeyer die Struktur für eine heteroaromatische
Verbindung vor, die die organische und medizinische Chemie nachhaltig veränderte: Indol …

Glycerol as an efficient promoting medium for organic reactions

Y Gu, J Barrault, F Jerome - Advanced synthesis & catalysis, 2008 - Wiley Online Library
Whereas the beneficial effect of water on reaction rate is decreased with an increase of the
reactant′ s hydrophobicity, we report here that the use of glycerol as solvent was able to …

Synthesis and biological evaluation of new piplartine analogues as potent aldose reductase inhibitors (ARIs)

VR Rao, P Muthenna, G Shankaraiah… - European journal of …, 2012 - Elsevier
As a continuation of our efforts directed towards the development of anti-diabetic agents
from natural sources, piplartine was isolated from Piper chaba, and was found to inhibit …

Sulfamic acid-catalyzed Michael addition of indoles and pyrrole to electron-deficient nitroolefins under solvent-free condition

LT An, JP Zou, LL Zhang, Y Zhang - Tetrahedron Letters, 2007 - Elsevier
Sulfamic acid-catalyzed Michael addition of indoles and pyrrole to electron-deficient nitroolefins
under solvent-free condition - ScienceDirect Skip to main contentSkip to article Elsevier logo …

B(C6F5)3-Catalyzed Michael Reactions: Aromatic C–H as Nucleophiles

W Li, T Werner - Organic letters, 2017 - ACS Publications
The Michael reaction is a widely used reaction for the C–C coupling of electron-poor olefins
and C (sp3)–H pronucleophiles. Herein we report the Michael reaction between alkenes …

Silica-supported sodium sulfonate with ionic liquid: a neutral catalyst system for Michael reactions of indoles in water

Y Gu, C Ogawa, S Kobayashi - Organic Letters, 2007 - ACS Publications
A neutral catalytic system for Michael reactions of indoles has been developed by combining
silica-supported benzenesulfonic acid sodium salt with hydrophobic ionic liquid in water. An …

Metal-Free Dehydrogenative Double C–H Sulfuration To Access Thieno[2,3-b]indoles Using Elemental Sulfur

J Liu, Y Zhang, Y Yue, Z Wang, H Shao… - The Journal of …, 2019 - ACS Publications
We report a base-promoted metal-free approach for the synthesis of thieno [2, 3-b] indole
derivatives. This method combined four C–H σ-bond cleavage reactions of two different …

Friedel–Crafts alkylation reaction with fluorinated alcohols as hydrogen-bond donors and solvents

RJ Tang, T Milcent, B Crousse - RSC advances, 2018 - pubs.rsc.org
An effective and clean FC alkylation of indoles and electron-rich arenes with β-nitroalkenes
in HFIP was reported. The desired products are formed rapidly in excellent yields under mild …