In this review, we focus on the potential role of the γ-aminobutyric acidergic (GABAergic)
system in age-related episodic memory impairments in humans, with a particular focus on …

Alzheimer's disease (AD) is a neurodegenerative disorder characterized clinically by severe
cognitive deficits and pathologically by amyloid plaques, neuronal loss, and neurofibrillary …

NG2 glia, also known as oligodendrocyte precursor cells (OPCs), play an important role in
proliferation and give rise to myelinating oligodendrocytes during early brain development …

The hippocampus is one of a group of remarkable structures embedded within the brain's
medial temporal lobe. Long known to be important for memory, it has been a prime focus of …

Neuroscience produces a vast amount of data from an enormous diversity of neurons. A
neuronal classification system is essential to organize such data and the knowledge that is …

The performance of the brain is constrained by wiring length and maintenance costs. The
apparently inverse relationship between number of neurons in the various interneuron …

GABA is the main inhibitory neurotransmitter in the adult forebrain, where it activates
ionotropic type A and metabotropic type B receptors. Early studies have shown that GABAA …

Hippocampome. org is a comprehensive knowledge base of neuron types in the rodent
hippocampal formation (dentate gyrus, CA3, CA2, CA1, subiculum, and entorhinal cortex) …

Synaptic dysfunction is widely proposed as an initial insult leading to the neurodegeneration
observed in Alzheimer's disease (AD). We hypothesize that the initial insult originates in the …

The basal ganglia network serves to integrate information about context, actions, and
outcomes to shape the behavior of an animal based on its past experience. Clinically, the …