Critical loss: the effects of VEuPathDB defunding on global health

C Fernandez-Prada, NS Moretti… - The Lancet …, 2025 - thelancet.com
The scientific community worldwide is shocked by the recent announcement on the
EuPathDB website, which states that the National Institute of Allergy and Infectious Diseases …

Identification of a unique conserved region from a kinetoplastid genome of Leishmania orientalis (formerly named Leishmania siamensis) strain PCM2 in Thailand

P Anuntasomboon, S Siripattanapipong, S Unajak… - Scientific Reports, 2023 - nature.com
Mitochondrial DNAs (mtDNAs) appear in almost all eukaryotic species and are useful
molecular markers for phylogenetic studies and species identification. Kinetoplast DNAs …

Genomic and epidemiological evidence for the emergence of a putative L. donovani/L. infantum hybrid with unusual epidemiology in Northern Italy

F Bruno, G Castelli, B Li, S Reale, E Carra, F Vitale… - bioRxiv, 2023 - biorxiv.org
Leishmania (L.) infantum is the main causative agent of animal and human leishmaniasis in
the Mediterranean basin. Despite its clinical significance, little is known on the genetic …

Genomic and epidemiological evidence for the emergence of a L. infantum/L. donovani hybrid with unusual epidemiology in northern Italy

F Bruno, G Castelli, B Li, S Reale, E Carra, F Vitale… - Mbio, 2024 - Am Soc Microbiol
Leishmania (L.) infantum is one of the main causative agents of animal and human
leishmaniasis across many endemic areas in South America, Europe, North Africa, and Asia …

Assembly of a Large Collection of Maxicircle Sequences and Their Usefulness for Leishmania Taxonomy and Strain Typing

JC Solana, C Chicharro, E García, B Aguado, J Moreno… - Genes, 2022 - mdpi.com
Parasites of medical importance, such as Leishmania and Trypanosoma, are characterized
by the presence of thousands of circular DNA molecules forming a structure known as …

Revisiting the heterogeneous global genomic population structure of Leishmania infantum

LH Patino, A Castillo-Castañeda… - Microbial …, 2021 - microbiologyresearch.org
Leishmania infantum is the main causative agent responsible for visceral leishmaniasis
(VL), a disease with global distribution. The genomic structure and genetic variation of this …

GIP: an open-source computational pipeline for mapping genomic instability from protists to cancer cells

GF Späth, G Bussotti - Nucleic Acids Research, 2022 - academic.oup.com
Genome instability has been recognized as a key driver for microbial and cancer adaptation
and thus plays a central role in many diseases. Genome instability encompasses different …

A comparative genomics approach reveals a local genetic signature of Leishmania tropica in Morocco

H Talimi, O Daoui, G Bussotti, I Mhaidi… - Microbial …, 2024 - microbiologyresearch.org
In Morocco, cutaneous leishmaniasis (CL) caused by Leishmania (L.) tropica is an important
health problem. Despite the high incidence of CL in the country, the genomic heterogeneity …

ITS1 and cpb genetic polymorphisms in Algerian and Tunisian Leishmania infantum isolates from humans and dogs

R Benikhlef, M Chaouch, MB Abid… - Zoonoses and Public …, 2023 - Wiley Online Library
Abstract Leishmania (L.) infantum strains, isolated from varying hosts and clinical
manifestations (cutaneous, visceral and canine leishmaniasis), were investigated in order to …

Diversity, Abundance and Leishmania infantum Infection Rate of Phlebotomine Sandflies in an Area with Low Incidence of Visceral Leishmaniasis in Northern Tunisia

M Weslati, J Ghrab, M Benabid, O Souissi, K Aoun… - Microorganisms, 2022 - mdpi.com
We report the study of sandfly Leishmania infection in an area of low incidence of visceral
leishmaniasis in Tunisia. Sandflies were collected monthly using CDC light-traps set in …