Despite considerable research efforts, inflammatory diseases remain a heavy burden on
human health, causing significant economic losses annually. Histone deacetylases …

Atherosclerosis (AS) features include progressive hardening and reduced elasticity of
arteries. AS is the leading cause of morbidity and mortality. An increasing amount of …

Overproduction of reactive oxygen species (ROS) is a well-established indicator of ongoing
tissue inflammation. However, there is a scarcity of molecular imaging probes capable of …

Background Chronic lung disease resulting from dysfunctional cystic fibrosis
transmembrane conductance regulator (CFTR) and NFκB-mediated neutrophilic …

Hepatic injury occurs frequently during sepsis, and polysaccharides isolated from plants
have been reported to have antiinflammatory and antioxidant effects in various models …

Trauma remains a leading cause of morbidity and mortality among all age groups in the
United States. Hemorrhagic shock and traumatic brain injury (TBI) are major causes of …

The Chilean strawberry fruit has high content of antioxidants and polyphenols. Previous
studies evidenced antioxidant properties by in vitro methods. However, the antioxidant effect …

Hepatic ischemia-reperfusion injury (HIRI) is a major clinical cause of morbidity and mortality
in liver surgery and transplantation. Many studies have found that nitric oxide (NO) plays an …

Histone deacetylase inhibitors (HDACi) induce potent anti-inflammatory responses when
used to treat inflammatory diseases. Suberoylanilide hydroxamic acid (SAHA), a pan …

Objective (s): In the present study, our aim was to investigate the possible protective effects
of epigallocatechin gallate (EGCG) on lipopolysaccharide (LPS)-induced hepatotoxicity by …