Developmental trajectories of early life stress and trauma: a narrative review on neurobiological aspects beyond stress system dysregulation

A Agorastos, P Pervanidou, GP Chrousos… - Frontiers in …, 2019 - frontiersin.org
Early life stressors display a high universal prevalence and constitute a major public health
problem. Prolonged psychoneurobiological alterations as sequelae of early life stress (ELS) …

Current research trends in early life stress and depression: Review of human studies on sensitive periods, gene–environment interactions, and epigenetics

C Heim, EB Binder - Experimental neurology, 2012 - Elsevier
Early life stress, such as childhood abuse, neglect and loss, is a well established major risk
factor for developing depressive disorders later in life. We here summarize and discuss …

Association of disrupted circadian rhythmicity with mood disorders, subjective wellbeing, and cognitive function: a cross-sectional study of 91 105 participants from the …

LM Lyall, CA Wyse, N Graham, A Ferguson… - The Lancet …, 2018 - thelancet.com
Background Disruption of sleep and circadian rhythmicity is a core feature of mood disorders
and might be associated with increased susceptibility to such disorders. Previous studies in …

Emotion regulation mediates the relationship between ACES and physical and mental health.

M Cloitre, C Khan, MA Mackintosh… - … , Practice, and Policy, 2019 - psycnet.apa.org
Objective: Adverse Childhood Experiences (ACEs) have consistently been associated with a
range of negative psychological and physical outcomes in adulthood. Despite the strength of …

Risky families: family social environments and the mental and physical health of offspring.

RL Repetti, SE Taylor, TE Seeman - Psychological bulletin, 2002 - psycnet.apa.org
Risky families are characterized by conflict and aggression and by relationships that are
cold, unsupportive, and neglectful. These family characteristics create vulnerabilities and/or …

[图书][B] Patient-centered medicine: transforming the clinical method

M Stewart, JB Brown, WW Weston, T Freeman… - 2024 - books.google.com
The Patient-Centered Clinical Method (PCCM) has been a core tenet of the practice and
teaching of medicine since the first edition of Patient-Centered Medicine-Transforming the …

The role of early life stress as a predictor for alcohol and drug dependence

MA Enoch - Psychopharmacology, 2011 - Springer
Rationale Genetic and environmental influences on the development of alcohol and drug
dependence are equally important. Exposure to early life stress, that is unfortunately …

[PDF][PDF] Ending violence against women

WIGB Violence - Issues in World Health, 1999 - xyonline.net
Around the world at least one woman in every three has been beaten, coerced into sex, or
otherwise abused in her lifetime. Most often the abuser is a member of her own family …

Separate and cumulative effects of adverse childhood experiences in predicting adult health and health care utilization

MJ Chartier, JR Walker, B Naimark - Child abuse & neglect, 2010 - Elsevier
OBJECTIVES: Objectives of this population-based study were:(1) to examine the relative
contribution of childhood abuse and other adverse childhood experiences to poor adult …

Long-term physical and mental health consequences of childhood physical abuse: Results from a large population-based sample of men and women

KW Springer, J Sheridan, D Kuo, M Carnes - Child abuse & neglect, 2007 - Elsevier
OBJECTIVE: Child maltreatment has been linked to negative adult health outcomes;
however, much past research includes only clinical samples of women, focuses exclusively …