Abstract Engrailed2 (En2) is a transcription factor that transfers from cell to cell through
unconventional pathways. The poorly understood internalization mechanism of this cationic …

Uremic toxins exert pathophysiological effects on cells and tissues, such as the generation
of a pro-calcifying subtype of exosome-like extracellular vesicles (EVs) in vascular cells …

Although glycosaminoglycan (GAG)–protein interactions are important in many
physiological and pathological processes, the structural requirements for binding are poorly …

Pingyangmycin is an anticancer drug known as bleomycin A5 (A5), discovered in the
Pingyang County of Zhejiang Province of China. Bleomycin (BLM) is a mixture of mainly two …

Citrate-coated iron oxide nanoparticles, specifically Synomag®-COOH (SynC), are
promising tracers in magnetic particle imaging (MPI) due to their high magnetic moments …

Abstract Background/Aims: Bleomycin is a clinically used anti-cancer drug that produces
DNA breaks once inside of cells. However, bleomycin is a positively charged molecule and …

Pingyangmycin is a clinically used anticancer drug and induces lung fibrosis in certain
cancer patients. We previously reported that the negatively charged cell surface …

Voltage‐gated proton channels (HV1) have been found in many mammalian cells and play
a crucial role in the immune system, male fertility, and cancer progression …

Abstract Engrailed-2 (En2) is a transcription factor that possesses as most homeoproteins
the unique and intriguing property to transfer from cell to cell through unconventional …

Heparanase is an endo-beta-glucuronidase, the only enzyme in mammals capable of
cleaving heparan sulfate/heparin chains from proteoglycans. The oligosaccharides …