Cells are the basic units of all living matter which harness the flow of energy to drive the
processes of life. While the biochemical networks involved in energy transduction are well …

We lay the foundation of a circuit theory for chemical reaction networks. Chemical reactions
are grouped into chemical modules solely characterized by their current-concentration …

Combinatorial pathway optimization is an important tool in metabolic flux optimization.
Simultaneous optimization of a large number of pathway genes often leads to combinatorial …

Generalizing response theory of open systems far from equilibrium is a central quest of
nonequilibrium statistical physics. Using stochastic thermodynamics, we develop an …

The precision of currents in Markov networks is bounded by dissipation via the so-called
thermodynamic uncertainty relation (TUR). In our Letter, we demonstrate a similar inequality …

We generalize the thermodynamic uncertainty relation (TUR) and thermodynamic speed
limit (TSL) for deterministic chemical reaction networks (CRNs). The scaled diffusion …

Information thermodynamics relates the rate of change of mutual information between two
interacting subsystems to their thermodynamics when the joined system is described by a …

All current formulations of nonequilibrium thermodynamics of open chemical reaction
networks rely on the assumption of non-interacting species. We develop a general theory …

Chemical reaction networks offer a natural nonlinear generalization of linear Markov jump
processes on a finite state-space. In this paper, we analyze the dynamical large deviations …

Current formulations of nonequilibrium thermodynamics of open chemical reaction networks
only consider chemostats as free-energy sources sustaining nonequilibrium behaviors …