The objective of this review is an attempt to emphasize the development in the chemistry
and to display review of diverse therapeutic actions of cardiac glycosides. Anticancer activity …

Abstract (25R)-spirost-5-en-3β-ol, also known as diosgenin (DSG), exerts antiproliferative
activity on diverse cell lines, induces apoptosis, and acts as a chemopreventative agent …

We developed new iminosugar-based glycosidase inhibitors against SARS-CoV-2. Known
drugs (miglustat, migalastat, miglitol, and swainsonine) were chosen as lead compounds to …

Chemical studies on Ibervillea sonorae (S. Watson) Greene root led to isolation and
chemical characterization of diverse cucurbitacin triterpenoid compounds such as kinoin A …

Diosgenin has been modified to furostane derivatives after opening the F-spiroacetal ring.
The aldehyde group at C26 in derivative 8 was unexpectedly transformed to the ketone 9 …

Five new derivatives of macrolide antibiotic Brefeldin A (BFA, 6), named as Brefeldin E1–E5
(1–5), along with Brefeldin A 7-O-acetate (7), mycotoxins (8–9) and mangrovamides A (10) …

Diverse steroidal compounds have shown antiproliferative activity on certain tumor cell lines;
however, their complete role on cancer cells has not been extensively established since the …

Spirostanes, family of steroidal sapogenins continue to attract attention of organic chemists
due to their easily occurring cleavage reactions in F ring and because of the renaissance of …

Based on the fact that Timosaponin A-III, a saponin isolated from the rhizome of
Anemarrhena asphodeloides, is a promising bioactive lead compound in the treatment of …

Three pairs of enantiomeric neolignans 1a/1b–3a/3b were isolated from the stems of
Picrasma quassioides, and separated successfully by chiral-phase HPLC. Their structures …