Biosensing with dnazymes

EM McConnell, I Cozma, Q Mou, JD Brennan… - Chemical Society …, 2021 - pubs.rsc.org
This article provides a comprehensive review of biosensing with DNAzymes, providing an
overview of different sensing applications while highlighting major progress and seminal …

Development of the DNA-based biosensors for high performance in detection of molecular biomarkers: More rapid, sensitive, and universal

Q Wang, J Wang, Y Huang, Y Du, Y Zhang… - Biosensors and …, 2022 - Elsevier
The molecular biomarkers are molecules that are closely related to specific physiological
states. Numerous molecular biomarkers have been identified as targets for disease …

DNAzyme biosensors for the detection of pathogenic bacteria

X Ma, W Ding, C Wang, H Wu, X Tian, M Lyu… - Sensors and Actuators B …, 2021 - Elsevier
Pathogenic bacteria contamination can cause many problems, such as infections in humans
and animals and environmental pollution. Early prevention and detection of pathogenic …

UV-fluorescence probe for detection Ni2+ with colorimetric/spectral dual-mode analysis method and its practical application

Y Zhang, Y Zhao, B Song, K Liu, J Gu, Y Yue… - Bioorganic …, 2021 - Elsevier
Fluorescence probe combines with fluorescence imaging technology has become the most
powerful analytical method with their great advantages of high sensitivity and selectivity and …

Functional nucleic acid-based fluorescent probes for metal ion detection

J Xu, R Jiang, Y Feng, Z Liu, J Huang, C Ma… - Coordination Chemistry …, 2022 - Elsevier
Metal ions are ubiquitous elements within our environments. Their excessive accumulation
poses a great threat to human health. With the development of biology and bioanalytical …

Recent Advances on DNAzyme‐Based Sensing

Z Huang, X Wang, Z Wu… - Chemistry–An Asian …, 2022 - Wiley Online Library
Owing to the high sensitivity, excellent programmability, and flexible obtainment through in
vitro selection, RNA‐cleaving DNAzymes have attracted increasing interest in developing …

Ultra-sensitive DNAzyme-based optofluidic biosensor with liquid crystal-Au nanoparticle hybrid amplification for molecular detection

Z Wang, Y Liu, H Wang, S Wang, K Liu, T Xu… - Sensors and Actuators B …, 2022 - Elsevier
Due to the specific cofactor dependence and the potent catalytic capability, DNAzymes have
shown great promise in the application of biosensors. However, it poses significant …

High Catalytic Activity of Fluorophore-Labeled Y-Shaped DNAzyme/3D MOF-MoS2NBs as a Versatile Biosensing Platform for the Simultaneous Detection of Hg2+, Ni2+, and …

R Pavadai, A Amalraj, S Subramanian… - ACS Applied Materials …, 2021 - ACS Publications
In this study, we have designed a three-fluorophore-labeled Y-shaped DNAzyme with a high
catalytic cleavage activity and a three-dimensional (3D) MOF-MoS2NB (metal–organic …

A triple amplification strategy using GR-5 DNAzyme as a signal medium for ultrasensitive detection of trace Pb2+ based on CRISPR/Cas12a empowered …

Y Yue, S Wang, Q Jin, N An, L Wu, H Huang - Analytica Chimica Acta, 2023 - Elsevier
Abstract Lead ions (Pb 2+) are a well-known toxic heavy metal that poses a significant threat
to human health. Therefore, the development of a simple and ultrasensitive technique for …

Zn2+‐Dependent DNAzymes: From Solution Chemistry to Analytical, Materials and Therapeutic Applications

WJ Moon, Y Yang, J Liu - ChemBioChem, 2021 - Wiley Online Library
Since 1994, deoxyribozymes or DNAzymes have been in vitro selected to catalyze various
types of reactions. Metal ions play a critical role in DNAzyme catalysis, and Zn2+ is a very …