Sporotrichosis in immunocompromised hosts

F Queiroz-Telles, R Buccheri, G Benard - Journal of Fungi, 2019 - mdpi.com
Sporotrichosis is a global implantation or subcutaneous mycosis caused by several
members of the genus Sporothrix, a thermo-dimorphic fungus. This disease may also depict …

The Role of Macrophages in the Host's Defense against Sporothrix schenckii

E Ruiz-Baca, A Pérez-Torres, Y Romo-Lozano… - Pathogens, 2021 - mdpi.com
The role of immune cells associated with sporotrichosis caused by Sporothrix schenckii is
not yet fully clarified. Macrophages through pattern recognition receptors (PRRs) can …

Differential Recognition of Sporothrix schenckii, Sporothrix brasiliensis, and Sporothrix globosa by Human Monocyte-Derived Macrophages and Dendritic Cells

M Gómez-Gaviria, I Martínez-Duncker… - Infection and Drug …, 2023 - Taylor & Francis
Background Sporotrichosis is a mycosis frequently caused by Sporothrix schenckii,
Sporothrix brasiliensis, and Sporothrix globosa. The cell wall is a species-specific fungal …

Immunopathogenesis of human sporotrichosis: what we already know

F Conceição-Silva, FN Morgado - Journal of fungi, 2018 - mdpi.com
Sporotrichosis is a subacute/chronic mycosis caused by dimorphic fungus of the genus
Sporothrix. This mycosis may affect both human and domestic animals and in the last few …

Comparative efficacy and toxicity of two vaccine candidates against Sporothrix schenckii using either Montanide™ Pet Gel A or aluminum hydroxide adjuvants in mice

DL Portuondo, A Batista-Duharte, LS Ferreira… - Vaccine, 2017 - Elsevier
Sporotrichosis is an important zoonosis in Brazil and the most frequent subcutaneous
mycosis in Latin America, caused by different Sporothrix species. Currently, there is no …

Dectin-1 expression by macrophages and related antifungal mechanisms in a murine model of Sporothrix schenckii sensu stricto systemic infection

JA Jellmayer, LS Ferreira, FA Manente… - Microbial …, 2017 - Elsevier
The available information about the role of Dectin-1 in sporotrichosis is scarce. Hence, we
aimed to assess Dectin-1 expression by macrophages and the activation of some related …

Experimental sporotrichosis in a cyclophosphamide-induced immunosuppressed mice model

FA Manente, C Quinello, LS Ferreira… - Medical …, 2018 - academic.oup.com
This report describes a model of host resistance for Sporothrix schenckii, an opportunistic
fungi in immunosuppressed mice with cyclophosphamide (CY) to be used in studies of …

Severe feline sporotrichosis associated with an increased population of CD8 low cells and a decrease in CD4 + cells

LHM Miranda, MA Santiago, TMP Schubach… - Medical …, 2016 - academic.oup.com
Sporotrichosis is a subcutaneous mycosis with worldwide distribution, especially in tropical
and subtropical areas. Zoonotic transmission is described with cats being the main animal …

Acute Penicillium marneffei infection stimulates host M1/M2a macrophages polarization in BALB/C mice

X Dai, C Mao, X Lan, H Chen, M Li, J Bai, J Deng… - BMC microbiology, 2017 - Springer
Background Penicillium marneffei (P. marneffei) is a thermally dimorphic fungus pathogen
that causes fatal infection. Alveolar macrophages are innate immune cells that have critical …

Molecular Components of the Sporothrix schenckii Complex that Induce Immune Response

CA Alba-Fierro, A Pérez-Torres, C Toriello… - Current …, 2016 - Springer
Sporotrichosis is a fungal disease caused by the Sporothrix schenckii complex that includes
species such as S. brasiliensis, S. schenckii sensu stricto, S. globosa, S. luriei, S. mexicana …