Fungal response to any stress is intricate, specific, and multilayered, though it employs only
a few evolutionarily conserved regulators. This comes with the assumption that one …

Treatment modalities for systemic mycoses are still limited. Currently, the main antifungal
therapeutics include polyenes, azoles, and echinocandins. However, even in the setting of …

Infections due to Aspergillus species are an acute threat to human health; members of the
Aspergillus section Fumigati are the most frequently occurring agents, but depending on the …

Aspergillus species contain pathogenic and opportunistic fungal pathogens which have the
potential to cause mycosis (invasive aspergillosis) in humans. The existing antifungal drugs …

The polyene antifungal amphotericin B (AmB) exerts a powerful and broad activity against a
vast array of fungi and in general displays a remarkably low rate of antimicrobial resistance …

Biological control mechanisms of plant diseases have been intensively studied. However,
how plant pathogens respond to and resist or alleviate biocontrol agents remains largely …

Amphotericin B (AMB), with widespread antifungal and anti-parasitic activities and low cross-
resistance with other drugs, has long been identified as a potent antimicrobial drug …

The polyene amphotericin B (AMB) exerts a powerful and broad antifungal activity. AMB acts
by (i) binding to ergosterol, leading to pore formation at the fungal plasma membrane with …

Antifungal susceptibility testing (AST) is crucial in clinical settings to guide appropriate
therapy. Nevertheless, discrepancies between treatment response and some results still …

Combinations of antifungal drugs can have synergistic antifungal activity, achieving high
therapeutic efficacy while minimizing the side effects. Amphotericin B (AMB) has been used …