Methods to discriminate between mechanism-based categories of pain experienced in the musculoskeletal system: a systematic review

MA Shraim, H Massé-Alarie, PW Hodges - Pain, 2021 - journals.lww.com
Mechanism-based classification of pain has been advocated widely to aid tailoring of
interventions for individuals experiencing persistent musculoskeletal pain. Three pain …

[HTML][HTML] Predicting chronic postsurgical pain: current evidence and a novel program to develop predictive biomarker signatures

KA Sluka, TD Wager, SP Sutherland, PA Labosky… - Pain, 2023 - journals.lww.com
Chronic pain affects more than 50 million Americans. Treatments remain inadequate, in
large part, because the pathophysiological mechanisms underlying the development of …

The neurobiology of central sensitization

SE Harte, RE Harris, DJ Clauw - Journal of Applied …, 2018 - Wiley Online Library
Central sensitization refers to the amplification of pain by central nervous system
mechanisms. Classically described as a consequence of ongoing nociceptive input, it is …

Chronic pain in the time of COVID‐19: stress aftermath and central sensitization

ER Serrano‐Ibáñez, R Esteve… - British Journal of …, 2021 - Wiley Online Library
Objectives The COVID‐19 crisis is a significant stressor worldwide. The physical and
emotional condition of individuals with pain sensitization syndromes who are experiencing …

Bad company: loneliness longitudinally predicts the symptom cluster of pain, fatigue, and depression in older adults

VD Powell, N Kumar, AT Galecki… - Journal of the …, 2022 - Wiley Online Library
Background Pain, fatigue, and depression frequently co‐occur as a symptom cluster. While
commonly occurring in those with cancer and autoimmune disease, the cluster is also found …

[HTML][HTML] Associations of psychologic factors with multiple chronic overlapping pain conditions

RB Fillingim, R Ohrbach, JD Greenspan… - Journal of oral & …, 2020 - ncbi.nlm.nih.gov
Aims: To characterize psychologic functioning across five chronic overlapping pain
conditions (COPCs)—temporomandibular disorders, fibromyalgia, low back pain, headache …

Approach to diagnosis and management of chronic pelvic pain in women: incorporating chronic overlapping pain conditions in assessment and management

SR Till, R Nakamura, A Schrepf… - … and Gynecology Clinics, 2022 - obgyn.theclinics.com
At least 15% to 20% of women suffer from chronic pelvic pain, which is defined as pain
occurring in the abdomen or pelvis for at least 14 days per month and is severe enough to …

Co-players in chronic pain: neuroinflammation and the tryptophan-kynurenine metabolic pathway

M Tanaka, N Török, F Tóth, Á Szabó, L Vécsei - Biomedicines, 2021 - mdpi.com
Chronic pain is an unpleasant sensory and emotional experience that persists or recurs
more than three months and may extend beyond the expected time of healing. Recently …

[HTML][HTML] Cannabidiol use for fibromyalgia: prevalence of use and perceptions of effectiveness in a large online survey

KF Boehnke, JJ Gagnier, L Matallana, DA Williams - The journal of pain, 2021 - Elsevier
Cannabidiol (CBD) is widely advertised as helpful for chronic pain management but
research is limited. Using a cross-sectional, anonymous survey, we examined patterns of …

Stimulated whole-blood cytokine/chemokine responses are associated with interstitial cystitis/bladder pain syndrome phenotypes and features of nociplastic pain: a …

A Schrepf, C Kaplan, RE Harris, DA Williams, DJ Clauw… - Pain, 2023 - journals.lww.com
Interstitial cystitis/bladder pain syndrome (IC/BPS) is a common and debilitating disease with
poor treatment outcomes. Studies from the multidisciplinary approach to the study of chronic …