[HTML][HTML] Metabolism shapes immune responses to Staphylococcus aureus
P Arumugam, T Kielian - Journal of Innate Immunity, 2024 - karger.com
Background: Staphylococcus aureus (S. aureus) is a common cause of hospital-and
community-acquired infections that can result in various clinical manifestations ranging from …
community-acquired infections that can result in various clinical manifestations ranging from …
Tissue niche influences immune and metabolic profiles to Staphylococcus aureus biofilm infection
Z Van Roy, P Arumugam, BP Bertrand… - Nature …, 2024 - nature.com
Infection is a devastating post-surgical complication, often requiring additional procedures
and prolonged antibiotic therapy. This is especially relevant for craniotomy and prosthetic …
and prolonged antibiotic therapy. This is especially relevant for craniotomy and prosthetic …
Bacterial single-cell RNA sequencing captures biofilm transcriptional heterogeneity and differential responses to immune pressure
LE Korshoj, T Kielian - Nature Communications, 2024 - nature.com
Biofilm formation is an important mechanism of survival and persistence for many bacterial
pathogens. These multicellular communities contain subpopulations of cells that display …
pathogens. These multicellular communities contain subpopulations of cells that display …
Tumor necrosis factor regulates leukocyte recruitment but not bacterial persistence during Staphylococcus aureus craniotomy infection
Background Craniotomy is a common neurosurgery used to treat intracranial pathologies.
Nearly 5% of the 14 million craniotomies performed worldwide each year become infected …
Nearly 5% of the 14 million craniotomies performed worldwide each year become infected …
Beyond Genes: Epiregulomes as Molecular Commanders in Innate Immunity
The natural fastest way to deal with pathogens or danger signals is the innate immune
system. This system prevents too much inflammation and tissue damage and efficiently …
system. This system prevents too much inflammation and tissue damage and efficiently …
Single-cell profiling reveals a conserved role for hypoxia-inducible factor signaling during human craniotomy infection
Z Van Roy, G Kak, LE Korshoj, JP Menousek… - Cell Reports …, 2024 - cell.com
Neurosurgeries complicated by infection are associated with prolonged treatment and
significant morbidity. Craniotomy is a common neurosurgical procedure; however, the …
significant morbidity. Craniotomy is a common neurosurgical procedure; however, the …
Staphyloccocus aureus biofilm, in absence of planktonic bacteria, produces factors that activate counterbalancing inflammatory and immune‐suppressive genes in …
RD Bell, EA Cann, B Mishra, M Valencia… - Journal of …, 2024 - Wiley Online Library
Staphyloccocus aureus (S. aureus) is a major bacterial pathogen in orthopedic
periprosthetic joint infection (PJI). S. aureus forms biofilms that promote persistent infection …
periprosthetic joint infection (PJI). S. aureus forms biofilms that promote persistent infection …
[引用][C] Metabolism Shapes Immune Responses
PAT Kielian - 2023 - europepmc.org
Background: Staphylococcus aureus (S. aureus) is a common cause of hospital-and
community-acquired infections that can result in various clinical manifestations ranging from …
community-acquired infections that can result in various clinical manifestations ranging from …