To date, vaccination has become one of the most effective strategies to control and reduce
infectious diseases, preventing millions of deaths worldwide. The earliest vaccines were …

While vaccination remains the most cost effective strategy for disease prevention,
communicable diseases persist as the second leading cause of death worldwide. There is a …

Helicobacter pylori induces symptomatic chronic gastritis in a subpopulation of infected
individuals. The mechanism (s) determining the development and severity of pathology …

To characterize posttreatment recurrence of Helicobacter pylori in Peru, 192 adults with H.
pylori–positive gastric biopsy specimens were monitored by 14C-Urea breath test, after …

Infection with the human gastric pathogen Helicobacter pylori can give rise to chronic
gastritis, peptic ulcer, and gastric cancer. All H. pylori strains express the surface-localized …

As the trend of antibiotic resistance has increased, prevention and treatment of Helicobacter
pylori infection have been challenged by the fact that no vaccines preventing H. pylori …

Over three decades have passed since the discovery of Helicobacter pylori (H. pylori), and
yet many questions about its treatment remain unanswered. For example, there is no …

Helicobacter pylori infection in the stomach is a common cause of peptic ulcer disease and
is a strong risk factor for the development of gastric adenocarcinoma, yet no effective …

Sublingual (SL) immunization has been described as an effective novel way to induce
mucosal immune responses in the respiratory and genital tracts. We examined the potential …

In the present study, we evaluated the capacity of Helicobacter pylori adhesin A (HpaA), a H.
pylori specific colonization factor, to induce therapeutic protection against H. pylori infection …