Antischistosomal agents: state of art and perspectives

EM Lago, RP Xavier, TR Teixeira, LM Silva… - Future Medicinal …, 2018 - Taylor & Francis
Praziquantel has remained the drug of choice for schistosomiasis chemotherapy for almost
40 years. The pressing need to develop a new antischistosomal drug may necessitate …

Therapeutic Potential of Natural Products in the Treatment of Schistosomiasis

CM Azevedo, CS Meira, JW da Silva, DMN Moura… - Molecules, 2023 - mdpi.com
It is estimated that 250 million people worldwide are affected by schistosomiasis. Disease
transmission is related to the poor sanitation and hygiene habits that affect residents of …

Phytochemical analysis of the essential oils from aerial parts of four Scutellaria “Skullcap” species cultivated in south Alabama: Scutellaria baicalensis Georgi, S …

SK Lawson, P Satyal… - Natural Product …, 2021 - journals.sagepub.com
Scutellaria (skullcap) are important medicinal plants. Scutellaria baicalensis and S. barbata
have been used in Chinese traditional medicine, while S. incana and S. lateriflora were …

Drug discovery and development for schistosomiasis

CR Caffrey, N El‐Sakkary, P Mäder… - … : drug discovery and …, 2019 - Wiley Online Library
Schistosomiasis is a neglected disease of poverty that is caused by several species of the
trematode flatworm, Schistosoma. Treatment relies on just one drug, the …

[HTML][HTML] In vitro antischistosomal activity of the Argemone mexicana methanolic extract and its main component berberine

JH Elizondo-Luévano, R Castro-Ríos… - Iranian Journal of …, 2021 - ncbi.nlm.nih.gov
Background: Schistosomiasis has been identified as a major public health problem in
tropical countries. The present study aimed to investigate the schistosomicidal effects of the …

Anti‐Schistosoma mansoni effects of essential oils and their components

MT Islam, M Martorell, B Salehi, WN Setzer… - Phytotherapy …, 2020 - Wiley Online Library
Schistosoma mansoni is endemic in 55 countries around the world. S. mansoni is a water‐
borne parasite of humans belonging to the group of blood flukes. Generally, schistosomiasis …

Assessment of tegumental damage to Schistosoma mansoni and S. haematobium after in vitro exposure to ferrocenyl, ruthenocenyl and benzyl derivatives of …

V Buchter, J Hess, G Gasser, J Keiser - Parasites & vectors, 2018 - Springer
Background Schistosomiasis is one of the most harmful parasitic diseases worldwide,
praziquantel being the only drug in widespread use to treat it. We recently demonstrated that …

Dealing with schistosomiasis: Current drug discovery strategies

S Gemma, S Federico, S Brogi, M Brindisi… - Annual Reports in …, 2019 - Elsevier
Schistosomiasis is one of the most prevalent parasitic diseases, accounting for heavy
socioeconomical and health burden in endemic countries. The control of this neglected …

Toxin-Pathogen Synergy Reshaping Detoxification and Antioxidant Defense Mechanism of Oligonychus afrasiaticus (McGregor)

AM AlJabr, A Hussain, M Rizwan-Ul-Haq - Molecules, 2018 - mdpi.com
Current study reveals the likelihood to use pathogen and toxin mutually as an effective and
eco-friendly strategy for Oligonychus afrasiaticus (McGregor) management, which could …

Barbatic acid from Cladia aggregata (lichen): Cytotoxicity and in vitro schistosomicidal evaluation and ultrastructural analysis against adult worms of Schistosoma …

H Silva, AL Aires, CLR Soares, JLF Sá, MCB Martins… - Toxicology in Vitro, 2020 - Elsevier
Schistosomiasis is one of the most significant neglected tropical diseases, affecting around
260 million people worldwide, and Praziquantel is currently the only available drug for the …