To accommodate daily recurring environmental changes, animals show cyclic variations in
behaviour and physiology, which include prominent behavioural states such as sleep–wake …

Circadian rhythms (CR) are a series of endogenous autonomous oscillators generated by
the molecular circadian clock which acting on coordinating internal time with the external …

Despite the steady increase in the number of studies focusing on the development of tissue
engineered constructs, solutions delivered to the clinic are still limited. Specifically, the lack …

Studies in shift workers and model organisms link circadian disruption to breast cancer.
However, molecular circadian rhythms in noncancerous and cancerous human breast …

Breast cancer is the most common type of cancer worldwide and one of the major causes of
cancer death in women. Epidemiological studies have established a link between night-shift …

Transmission and secretion of signals via the choroid plexus (ChP) brain barrier can
modulate brain states via regulation of cerebrospinal fluid (CSF) composition. Here, we …

The extracellular matrix (ECM) is a dynamic structural network that provides a physical
scaffolding, as well as biochemical factors that maintain normal tissue homeostasis and thus …

The extracellular matrix (ECM) is present in all solid tissues and considered a master
regulator of cell behaviour and phenotype. The importance of maintaining the correct …

The circadian clock temporally organizes cellular physiology throughout the day, allowing
daily environmental changes to be anticipated and potentially harmful physiologic …

The mammalian circadian clockwork has evolved as a timing system that allows the daily
environmental changes to be anticipated so that behavior and tissue physiology can be …