Metabolic reprogramming is a common hallmark of cancers and involves alterations in many
metabolic pathways during tumor initiation and progression. However, the cancer-specific …

Although biologically targeted therapies based on key oncogenic mutations have made
significant progress in the treatment of locally advanced or metastatic thyroid cancer, the …

Introduction Papillary thyroid carcinomas (PTC) are the most common thyroid malignancies
that are often diagnosed as microcarcinomas when the tumor is less than one centimetre in …

Acetaminophen (APAP) overdose is a major cause of drug‐induced liver injury. Sirtuins 5
(SIRT5) has been implicated in the development of various liver diseases. However, its …

Thyroid cancer is the most common malignant tumor of the endocrine system, and evidence
suggests that post-translational modifications (PTMs) and epigenetic alterations play an …

Abstract lncRNA ZFAS1 was identified to facilitate thyroid cancer, but its role in medullary
thyroid carcinoma (MTC) remains unknown. This study aimed to unravel the potential …

Objective This study was designed to investigate the regulatory effects of kinesin family
member (KIF) 23 on anaplastic thyroid cancer (ATC) cell viability and migration and the …

Abstract Non-Small Cell Lung Cancer (NSCLC) is the most prevalent kind of lung cancer
with around 85% of total lung cancer cases. Despite vast therapies being available, the …

摘要目的: 探究SIRT7 基因琥珀酰化修饰对肝癌患者的生存, 免疫浸润及预后的相关性分析.
方法: 采用生物信息分析法对SIRT7 在肝癌组织中的表达情况及其对肝癌患者预后的影响进行 …

The microbial flora has always been a center of interest for the identification of novel
bioactive secondary metabolites (SMs) used against a diversity of infections and ailments …