An endogenously activated antiviral state restricts SARS-CoV-2 infection in differentiated primary airway epithelial cells
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of the
coronavirus disease-19 (COVID-19) pandemic, was identified in late 2019 and caused> 5 …
coronavirus disease-19 (COVID-19) pandemic, was identified in late 2019 and caused> 5 …
The C-terminal PARP domain of the long ZAP isoform contributes essential effector functions for CpG-directed antiviral activity
D Kmiec, MJ Lista-Brotos, M Ficarelli, CM Swanson… - bioRxiv, 2021 - biorxiv.org
The zinc finger antiviral protein (ZAP) is a broad inhibitor of virus replication. Its best-
characterized function is to bind CpG dinucleotides present in viral RNA and, through the …
characterized function is to bind CpG dinucleotides present in viral RNA and, through the …