cis-Regulatory Elements in Plant Development, Adaptation, and Evolution

AP Marand, AL Eveland, K Kaufmann… - Annual review of …, 2023 - annualreviews.org
cis-Regulatory elements encode the genomic blueprints that ensure the proper
spatiotemporal patterning of gene expression necessary for appropriate development and …

Cis-regulatory sequences in plants: their importance, discovery, and future challenges

RJ Schmitz, E Grotewold, M Stam - The plant cell, 2022 - academic.oup.com
The identification and characterization of cis-regulatory DNA sequences and how they
function to coordinate responses to developmental and environmental cues is of paramount …

Plant pan-genomes are the new reference

PE Bayer, AA Golicz, A Scheben, J Batley, D Edwards - Nature plants, 2020 - nature.com
Recent years have seen a surge in plant genome sequencing projects and the comparison
of multiple related individuals. The high degree of genomic variation observed led to the …

Widespread long-range cis-regulatory elements in the maize genome

WA Ricci, Z Lu, L Ji, AP Marand, CL Ethridge… - Nature plants, 2019 - nature.com
Genetic mapping studies on crops suggest that agronomic traits can be controlled by gene–
distal intergenic loci. Despite the biological importance and the potential agronomic utility of …

The prevalence, evolution and chromatin signatures of plant regulatory elements

Z Lu, AP Marand, WA Ricci, CL Ethridge, X Zhang… - Nature Plants, 2019 - nature.com
Chromatin accessibility and modification is a hallmark of regulatory DNA, the study of which
led to the discovery of cis-regulatory elements (CREs). Here, we characterize chromatin …

Genomic innovation for crop improvement

MW Bevan, C Uauy, BBH Wulff, J Zhou, K Krasileva… - Nature, 2017 - nature.com
Crop production needs to increase to secure future food supplies, while reducing its impact
on ecosystems. Detailed characterization of plant genomes and genetic diversity is crucial …

Reconstructing the maize leaf regulatory network using ChIP-seq data of 104 transcription factors

X Tu, MK Mejía-Guerra, JA Valdes Franco… - Nature …, 2020 - nature.com
The transcription regulatory network inside a eukaryotic cell is defined by the combinatorial
actions of transcription factors (TFs). However, TF binding studies in plants are too few in …

Scaling by shrinking: empowering single-cell'omics' with microfluidic devices

SM Prakadan, AK Shalek, DA Weitz - Nature Reviews Genetics, 2017 - nature.com
Recent advances in cellular profiling have demonstrated substantial heterogeneity in the
behaviour of cells once deemed'identical', challenging fundamental notions of …

On the road to breeding 4.0: unraveling the good, the bad, and the boring of crop quantitative genomics

JG Wallace, E Rodgers-Melnick… - Annual review of …, 2018 - annualreviews.org
Understanding the quantitative genetics of crops has been and will continue to be central to
maintaining and improving global food security. We outline four stages that plant breeding …

Profiling of accessible chromatin regions across multiple plant species and cell types reveals common gene regulatory principles and new control modules

KA Maher, M Bajic, K Kajala, M Reynoso… - The Plant …, 2018 - academic.oup.com
The transcriptional regulatory structure of plant genomes remains poorly defined relative to
animals. It is unclear how many cis-regulatory elements exist, where these elements lie …