Arsenic trioxide: insights into its evolution to an anticancer agent
Arsenic and its various forms have been in use in ancient Chinese medicine for more than
2000 years. Arsenicals have gained importance for having remedial effects for various …
2000 years. Arsenicals have gained importance for having remedial effects for various …
[HTML][HTML] Molecular docking, validation, dynamics simulations, and pharmacokinetic prediction of natural compounds against the SARS-CoV-2 main-protease
C Shivanika, D Kumar, V Ragunathan… - … structure & dynamics, 2020 - ncbi.nlm.nih.gov
The study aims to evaluate the potency of two hundred natural antiviral phytocompounds
against the active site of the Severe Acquired Respiratory Syndrome-Coronavirus− 2 (SARS …
against the active site of the Severe Acquired Respiratory Syndrome-Coronavirus− 2 (SARS …
Role of azoles in cancer prevention and treatment: present and future perspectives
Background: Cancer has gradually become one of the leading causes of death worldwide.
The incidence of cancer among the population has increased alarmingly over the last two …
The incidence of cancer among the population has increased alarmingly over the last two …
p38α MAP kinase inhibitors to overcome EGFR tertiary C797S point mutation associated with osimertinib in non-small cell lung cancer (NSCLC): emergence of fourth …
The third-generation EGFR (epidermal growth factor receptor) inhibitors selectively and
irreversibly target EGFR-T790M and other activating EGFR mutations. Osimertinib is the only …
irreversibly target EGFR-T790M and other activating EGFR mutations. Osimertinib is the only …
Metabolites profiling and cheminformatics bioprospection of selected medicinal plants against the main protease and RNA-dependent RNA polymerase of SARS-CoV …
AA Lanrewaju, AM Enitan-Folami… - Journal of …, 2024 - Taylor & Francis
Despite the existence of some vaccines, SARS-CoV-2 (S-2) infections persist for various
reasons relating to vaccine reluctance, rapid mutation rate, and an absence of specific …
reasons relating to vaccine reluctance, rapid mutation rate, and an absence of specific …
Cheminformatics Bioprospection of Sunflower Seeds' Oils against Quorum Sensing System of Pseudomonas aeruginosa
NW S'thebe, JO Aribisala, S Sabiu - Antibiotics, 2023 - mdpi.com
Clinically significant pathogens such as Pseudomonas aeruginosa evade the effects of
antibiotics using quorum sensing (QS) systems, making antimicrobial resistance (AMR) a …
antibiotics using quorum sensing (QS) systems, making antimicrobial resistance (AMR) a …
Cheminformatics bioprospection of selected medicinal plants metabolites against trypsin cleaved VP4 (spike protein) of rotavirus A
AA Lanrewaju, AM Enitan-Folami… - Journal of …, 2024 - Taylor & Francis
Rotaviruses have continued to be the primary cause of acute dehydrating diarrhoea in
children under five years of age despite the global introduction of four World Health …
children under five years of age despite the global introduction of four World Health …
Natural products from Streptomyces spp. as potential inhibitors of the major factors (holoRdRp and nsp13) for SARS-CoV-2 replication: an in silico approach
The COVID-19 pandemic caused unprecedented damage to humanity, and while vaccines
have been developed, they are not fully effective against the SARS-CoV-2 virus. Limited …
have been developed, they are not fully effective against the SARS-CoV-2 virus. Limited …
Development of in silico protocols to predict structural insights into the metabolic activation pathways of xenobiotics
To establish in silico model to predict the structural insight into the metabolic bioactivation
pathway of xenobiotics, we considered two specific and one non-specific mammary …
pathway of xenobiotics, we considered two specific and one non-specific mammary …
Inhibition Kinetics and Theoretical Studies on Zanthoxylum chalybeum Engl. Dual Inhibitors of α-Glucosidase and α-Amylase
Compounds from Zanthoxylum chalybeum Engl. were previously reported for inhibitory
activities of amylase and glucosidase enzymatic action on starch as a preliminary study …
activities of amylase and glucosidase enzymatic action on starch as a preliminary study …