Recent evidence indicates that ionizing radiation can enhance immune responses to
tumors. Advances in radiation delivery techniques allow hypofractionated delivery of …

Immunotherapy, particularly agents targeting the immunoregulatory PD-1/PD-L1 axis,
harnesses the power of the immune system to treat cancer, with unique potential for a …

Simple Summary Radiotherapy with carbon ions has been used for over 20 years in Asia
and Europe and is now planned in the USA. The physics advantages of carbon ions …

Quantitative lymphocyte alterations are frequent in patients with cancer, and strongly impact
prognosis and survival. The development of cancers in immunosuppressed patients has …

Background The COVID-19 pandemic hit all over the world, and cancer patients are more
vulnerable for COVID-19. The mortality rate may increase up to 25% in solid malignancies …

Background Cancer patients with coronavirus disease 2019 (COVID-19) have been
reported to have double the case fatality rate of the general population. Methods A …

Purpose Emerging evidence suggests a detrimental prognostic association between
radiation-induced lymphopenia (RIL) and pathologic response, progression-free survival …

Recent reports have shown that very high dose rate radiation (35–100 Gy/second) referred
to as FLASH tends to spare the normal tissues while retaining the therapeutic effect on …

Introduction Lymphopenia after radiotherapy has an adverse effect on the patient's outcome.
However, the relationship between radiotherapy dose delivery and lymphopenia is not fully …

Purpose Research to elucidate predictive factors of the abscopal effect is an essential first
step toward potentially modifying these factors to increase the incidence of systemic …