Identifying the Transients and Transformation Products in Hydroxyl Radical–Methimazole Reactions Using DFT and UPLC-Q-TOF MS/MS Approaches

KP Prasanthkumar, F Valayankadan… - The Journal of …, 2024 - ACS Publications
Oxidative reactions of the hydroxyl radical (· OH) with methimazole (MMI), an antithyroid
drug, are crucial for understanding its fate in oxidizing environments. By synergistically …

Reactivity of oxidants towards phenyl and benzyl substituted 5-selanylpentanoic acids: radiolytic and theoretical insights

BG Singh, KP Prasanthkumar, F Mangiavacchi… - New Journal of …, 2024 - pubs.rsc.org
Two selanyl compounds, 5-(phenylselanyl) pentanoic acid (1) and 5-(benzylselanyl)
pentanoic acid (2), were investigated for their reactivity towards one-electron oxidants …

Unravelling structures of radicals of kynurenic acid formed in the photoinduced reactions with tryptophan and N-acetyl tyrosine

OB Morozova, MP Geniman, MS Panov… - Physical Chemistry …, 2022 - pubs.rsc.org
Kynurenic acid (KNA) in the triplet state reacts with tryptophan (Trp) at neutral pH via proton-
coupled electron transfer (PCET), which includes the stepwise transition of both electron and …

Effect of Yarrowia lipolytica yeast biomass with increased kynurenic acid content on selected metabolic indicators in mice

M Matusiewicz, M Wróbel-Kwiatkowska, T Niemiec… - PeerJ, 2023 - peerj.com
Background The unconventional yeast species Yarrowia lipolytica is a valuable source of
protein and many other nutrients. It can be used to produce hydrolytic enzymes and …

Disproportionation and dimerisation of kynurenic acid under UV light

OB Morozova, YS Zhuravleva, MP Geniman… - … of Photochemistry and …, 2023 - Elsevier
In this work, we report on the photo-induced oxidation of kynurenic acid (KNA) by the triplet-
excited KNA in a neutral aqueous solution. This reaction is confirmed by two different time …

[PDF][PDF] МЕХАНИЗМЫ ПОВРЕЖДЕНИЯ АМИНОКИСЛОТЫ ТРИПТОФАН В РЕЗУЛЬТАТЕ РАДИКАЛЬНЫХ РЕАКЦИЙ, ФОТОИНДУЦИРОВАННЫХ …

ЮС ЖУРАВЛЕВА - kinetics.nsc.ru
Свободнорадикальная теория старения, предложенная в 1950-х годах XX века,
объясняла возрастную потерю функций органов и тканей накоплением необратимых …