Activated protein C assays: A review

J Oto, Á Fernández-Pardo, M Miralles, E Plana… - Clinica Chimica …, 2020 - Elsevier
Activated protein C (APC) acts as an “on demand” anticoagulant, reducing thrombin
formation. Reduced plasma levels of APC or protein C (PC) are associated with an …

[HTML][HTML] Inflammation, not hyperhomocysteinemia, is related to oxidative stress and hemostatic and endothelial dysfunction in uremia

D Mezzano, EO Pais, E Aranda, O Panes, P Downey… - Kidney international, 2001 - Elsevier
Inflammation, not hyperhomocysteinemia, is related to oxidative stress and hemostatic and
endothelial dysfunction in uremia. Background Several cardiovascular risk factors are …

Left ventricular thrombus and subsequent thromboembolism, comparison of anticoagulation, surgical removal, and antiplatelet agents

JM Lee, JJ Park, HW Jung, YS Cho, IY Oh… - … of atherosclerosis and …, 2013 - jstage.jst.go.jp
Aim: Left ventricular (LV) thrombus is one of the risk factors for systemic thromboembolism.
The aims of this study were to compare the long-term clinical outcomes of LV thrombus …

Chronic dialysis patients have high risk for pulmonary embolism

DP Tveit, IO Hypolite, P Hshieh, D Cruess… - American journal of …, 2002 - Elsevier
Pulmonary embolism has been considered uncommon in chronic dialysis patients, but has
not been adequately studied in a large population. In the US Renal Data System (USRDS) …

Activated protein C based therapeutic strategies in chronic diseases

F Bock, K Shahzad, N Vergnolle… - Thrombosis and …, 2014 - thieme-connect.com
Activated protein C (aPC) is a natural anticoagulant and a potent antiinflammatory and
cytoprotective agent. At the expense of increased bleeding risk aPC has been used–with …

Increase of neutrophil activation markers in venous thrombosis—Contribution of circulating activated protein C

L Martos, J Oto, Á Fernández-Pardo, E Plana… - International Journal of …, 2020 - mdpi.com
Upon activation, neutrophils release their content through different mechanisms like
degranulation and NETosis, thus prompting thrombosis. The natural anticoagulant activated …

Activated protein C levels in Behçet's disease and risk of venous thrombosis

S Navarro, JM Ricart, P Medina, A Vayá… - British journal of …, 2004 - Wiley Online Library
Behçet's disease is a multi‐systemic inflammatory disorder of unknown cause. Most
abnormalities have been associated with endothelial injury caused by vasculitis …

Carbon Nanofiber-Ionic Liquid Nanocomposite Modified Aptasensors Developed for Electrochemical Investigation of Interaction of Aptamer/Aptamer–Antisense Pair …

M Maral, A Erdem - Biosensors, 2023 - mdpi.com
Selective and sensitive detection of human activated protein C (APC) was performed herein
by using carbon nanofiber (CNF) and ionic liquid (IL) composite modified pencil graphite …

[HTML][HTML] Obesity is associated with increased morbidity after coronary artery bypass graft surgery in patients with renal insufficiency

DA Tolpin, CD Collard, VV Lee, MAA Elayda… - The Journal of thoracic …, 2009 - Elsevier
OBJECTIVE: Although obesity is a major risk factor for cardiovascular disease, it is not clear
whether obesity increases the risk of postoperative morbidity and mortality in patients …

Circulating levels of inflammatory cytokines (IL-1β and TNF-α), resistance to activated protein C, thrombin and fibrin generation in uncomplicated pregnancies

DHW Ku, YS Arkel, MP Paidas… - Thrombosis and …, 2003 - thieme-connect.com
We studied 33 women during normal uneventful pregnancies and with no history of previous
adverse pregnancy events for markers of activated coagulation and thrombin activity …