Pathophysiology, phenotypes and management of type 2 diabetes mellitus in Indian and Chinese populations

C Ke, KMV Narayan, JCN Chan, P Jha… - Nature Reviews …, 2022 - nature.com
Nearly half of all adults with type 2 diabetes mellitus (T2DM) live in India and China. These
populations have an underlying predisposition to deficient insulin secretion, which has a key …

The Lancet Commission on diabetes: using data to transform diabetes care and patient lives

JCN Chan, LL Lim, NJ Wareham, JE Shaw, TJ Orchard… - The Lancet, 2020 - thelancet.com
Executive summary 2020 will go down in history as the year when the global community was
awakened to the fragility of human health and the interdependence of the ecosystem …

[PDF][PDF] 中国2 型糖尿病防治指南(2013 年版)

翁建平 - 中华糖尿病杂志, 2014 - meditool.cn
随着经济高速发展和工业化进程的加速, 生活方式的改变和老龄化进程的加速,
使我国糖尿病的患病率正呈快速上升的趋势, 成为继心脑血管疾病, 肿瘤之后另一个严重危害 …

Standards of medical care for type 2 diabetes in China 2019

W Jia, J Weng, D Zhu, L Ji, J Lu, Z Zhou… - Diabetes/metabolism …, 2019 - Wiley Online Library
The prevalence of diabetes in China has increased rapidly from 0.67% in 1980 to 10.4% in
2013, with the aging of the population and westernization of lifestyle. Since its foundation in …

Mechanisms of diabetes mellitus-induced bone fragility

N Napoli, M Chandran, DD Pierroz… - Nature Reviews …, 2017 - nature.com
The risk of fragility fractures is increased in patients with either type 1 diabetes mellitus
(T1DM) or type 2 diabetes mellitus (T2DM). Although BMD is decreased in T1DM, BMD in …

Diabetes causes marked inhibition of mitochondrial metabolism in pancreatic β-cells

E Haythorne, M Rohm, M van de Bunt… - Nature …, 2019 - nature.com
Diabetes is a global health problem caused primarily by the inability of pancreatic β-cells to
secrete adequate levels of insulin. The molecular mechanisms underlying the progressive …

Understanding the mechanisms of reversal of type 2 diabetes

R Taylor, A Al-Mrabeh, N Sattar - The lancet Diabetes & …, 2019 - thelancet.com
Clinical and pathophysiological studies have shown type 2 diabetes to be a condition mainly
caused by excess, yet reversible, fat accumulation in the liver and pancreas. Within the liver …

Very low-calorie diet and 6 months of weight stability in type 2 diabetes: pathophysiological changes in responders and nonresponders

S Steven, KG Hollingsworth, A Al-Mrabeh… - Diabetes …, 2016 - Am Diabetes Assoc
OBJECTIVE Type 2 diabetes mellitus (T2DM) is generally regarded as an irreversible
chronic condition. Because a very low-calorie diet (VLCD) can bring about acute return to …

Oxidative stress and microvascular alterations in diabetic retinopathy: future therapies

ML Rodríguez, S Pérez, S Mena-Mollá… - Oxidative Medicine …, 2019 - Wiley Online Library
Diabetes is a disease that can be treated with oral antidiabetic agents and/or insulin.
However, patients' metabolic control is inadequate in a high percentage of them and a major …

C‐peptide determination in the diagnosis of type of diabetes and its management: A clinical perspective

E Maddaloni, GB Bolli, BM Frier… - Diabetes, Obesity …, 2022 - Wiley Online Library
Impaired beta‐cell function is a recognized cornerstone of diabetes pathophysiology.
Estimates of insulin secretory capacity are useful to inform clinical practice, helping to …