The role of IL-6/JAK2/STAT3 signaling pathway in cancers

B Huang, X Lang, X Li - Frontiers in oncology, 2022 - frontiersin.org
Interleukin-6 (IL-6) is a pleiotropic cytokine involved in immune regulation. It can activate
janus kinase 2 (JAK2)-signal transducer and activator of transcription 3 (STAT3) signaling …

Molecular principles of metastasis: a hallmark of cancer revisited

J Fares, MY Fares, HH Khachfe, HA Salhab… - Signal transduction and …, 2020 - nature.com
Metastasis is the hallmark of cancer that is responsible for the greatest number of cancer-
related deaths. Yet, it remains poorly understood. The continuous evolution of cancer …

Hypoxic glioma-derived exosomes promote M2-like macrophage polarization by enhancing autophagy induction

J Xu, J Zhang, Z Zhang, Z Gao, Y Qi, W Qiu, Z Pan… - Cell Death & …, 2021 - nature.com
Exosomes participate in intercellular communication and glioma microenvironment
modulation, but the exact mechanisms by which glioma-derived exosomes (GDEs) promote …

[HTML][HTML] Graphene-based nanomaterials for cancer therapy and anti-infections

Y Wang, J Li, X Li, J Shi, Z Jiang, CY Zhang - Bioactive materials, 2022 - Elsevier
Graphene-based nanomaterials (GBNMs) has been thoroughly investigated and extensively
used in many biomedical fields, especially cancer therapy and bacteria-induced infectious …

Effects of propofol on the development of cancer in humans

Y Xu, S Pan, W Jiang, F Xue, X Zhu - Cell Proliferation, 2020 - Wiley Online Library
Cancer is one of most the significant threats to human health worldwide, and the primary
method of treating solid tumours is surgery. Propofol, one of the most widely used …

METTL3 inhibition induced by M2 macrophage-derived extracellular vesicles drives anti-PD-1 therapy resistance via M6A-CD70-mediated immune suppression in …

J Ning, X Hou, J Hao, W Zhang, Y Shi… - Cell Death & …, 2023 - nature.com
The treatment options for advanced papillary thyroid cancer (PTC) and anaplastic thyroid
cancer (ATC) refractory to standard therapies are limited. Although anti-PD-1 therapy has a …

Inhaled anesthetics: environmental role, occupational risk, and clinical use

M Gaya da Costa, AF Kalmar, MMRF Struys - Journal of Clinical Medicine, 2021 - mdpi.com
Inhaled anesthetics have been in clinical use for over 150 years and are still commonly used
in daily practice. The initial view of inhaled anesthetics as indispensable for general …

Combinatorial photothermal 3D‐printing scaffold and checkpoint blockade inhibits growth/metastasis of breast cancer to bone and accelerates osteogenesis

C He, L Yu, H Yao, Y Chen… - Advanced Functional …, 2021 - Wiley Online Library
Cancer metastases are the main causes for the high mortality of cancer. The current
treatment modality for bone metastasis of breast cancer is dominantly destructive, which …

Trisulfide Bond‐Mediated Molecular Phototheranostic Platform for “Activatable” NIR‐II Imaging‐Guided Enhanced Gas/Chemo‐Hypothermal Photothermal Therapy

G Wu, F Liu, N Li, Q Fu, C Wang, S Yang… - Advanced …, 2023 - Wiley Online Library
Tumor microenvironment (TME)‐triggered phototheranostic platform offers a feasible
strategy to improve cancer diagnosis accuracy and minimize treatment side effects …

Biomimetic material degradation for synergistic enhanced therapy by regulating endogenous energy metabolism imaging under hypothermia

K Cheng, B Liu, XS Zhang, RY Zhang, F Zhang… - Nature …, 2022 - nature.com
Inefficient tumour treatment approaches often cause fatal tumour metastases. Here, we
report a biomimetic multifunctional nanoplatform explicitly engineered with a Co-based …