Autophagy, an intracellular conserved degradative process, plays a central role in the
renewal/recycling of a cell to maintain the homeostasis of nutrients and energy within the …

Cervical cancer has the second-highest incidence and mortality of female malignancy. The
major causes of mortality in patients with cervical cancer are invasion and metastasis. The …

Background: Despite the identification of autophagy-related protein 5 (ATG5) as a molecule
involved in the activated autophagy machinery during hepatitis B virus (HBV) infection and …

Abstract Bruceine D (BD) from Brucea javanica (L) exerts an antitumor effect in several
human cancers. At present, it has not been reported whether BD inhibits the malignancy of …

Autophagy pathway genes variants that play crucial roles in immune responses are involved
in many diseases but their role in viral diseases is ill-defined. ATG16L1 gene plays a crucial …

Background In response to intracellular pathogens, the autophagy gene IRGM plays an
essential role in the innate immune response. Various identified IRGM gene risk loci are …

Chronic hepatitis B virus (HBV) infection is related to chronic hepatitis, cirrhosis, and
hepatocellular carcinoma (HCC), and the interplay between the virus and host immune …

The heavy metal contamination like Cr (VI) has been increased by human activities and that
threats the ecosystem health of mangrove areas. Bioindicator is an emerging tool in the …

Objectives As a critical component of the autophagic machinery, autophagy‐related gene 5
(ATG5) is essential for autophagosome formation. Autophagy participates in the …

The autophagy process plays a cytoprotective role and ensures the healthy survival of a cell.
The role of autophagy has been implicated in various diseases, making it an essential …