Recent advances in understanding the biochemical and molecular mechanism of diabetic retinopathy

MS Ola, MI Nawaz, MM Siddiquei, S Al-Amro… - Journal of Diabetes and …, 2012 - Elsevier
One of the major complications in patients with diabetes is diabetic retinopathy (DR), a
leading cause of blindness worldwide. It takes several years before any clinical signs of …

Proteomic analysis and identification of aqueous humor proteins with a pathophysiological role in diabetic retinopathy

SY Chiang, ML Tsai, CY Wang, A Chen, YC Chou… - Journal of …, 2012 - Elsevier
Diabetic retinopathy (DR) can cause irreversible blindness and is the severest
microvascular complication in the eyes of patients with diabetic mellitus (DM). The …

A Prediction Model for Sight‐Threatening Diabetic Retinopathy Based on Plasma Adipokines among Patients with Mild Diabetic Retinopathy

Y An, B Cao, K Li, Y Xu, W Zhao… - Journal of Diabetes …, 2023 - Wiley Online Library
Background. Accumulating evidence has suggested a link between adipokines and diabetic
retinopathy (DR). This study is aimed at investigating the risk factors for sight‐threatening …

Traditional and novel risk factors of diabetic retinopathy and research challenges

GS Tan, M Kamran Ikram… - Current medicinal …, 2013 - ingentaconnect.com
Diabetic retinopathy affects one-third of people with diabetes and is the most frequent cause
of blindness in working aged adults. Although diabetic retinopathy blindness appears to …

[HTML][HTML] Adrenomedullin22-52 suppresses high-glucose-induced migration, proliferation, and tube formation of human retinal endothelial cells

Z Chen, G Liu, Y Xiao, P Lu - Molecular vision, 2014 - ncbi.nlm.nih.gov
Purpose To investigate the roles of an adrenomedullin receptor antagonist (adrenomedullin
22–52) on high-glucose-induced human retinal endothelial cell (HREC) in vitro cell biology …

[HTML][HTML] The association of serum leptin level and anthropometric measures with the severity of diabetic retinopathy in type 2 diabetes mellitus

M Afarid, A Attarzadeh, M Farvardin… - … and Innovation in …, 2018 - ncbi.nlm.nih.gov
This study was performed to determine the association amongst serum leptin level and
anthropometric measures with the severity of Diabetic Retinopathy (DR) in subjects with type …

Adrenomedullin Suppresses Vascular Endothelial Growth Factor–Induced Vascular Hyperpermeability and Inflammation in Retinopathy

A Imai, Y Toriyama, Y Iesato, K Hirabayashi… - The American Journal of …, 2017 - Elsevier
Diabetic macular edema (DME) is caused by blood-retinal barrier breakdown associated
with retinal vascular hyperpermeability and inflammation, and it is the major cause of visual …

[HTML][HTML] Development of a novel model of central retinal vascular occlusion and the therapeutic potential of the adrenomedullin–receptor activity–modifying protein 2 …

K Hirabayashi, M Tanaka, A Imai, Y Toriyama… - The American journal of …, 2019 - Elsevier
Central retinal vein occlusion (CRVO) is an intractable disease that causes visual acuity loss
with retinal ischemia, hemorrhage, and edema. In this study, we developed an experimental …

Identification of novel proliferative diabetic retinopathy related genes on protein–protein interaction network

J Zhang, J Yang, T Huang, Y Shu, L Chen - Neurocomputing, 2016 - Elsevier
Proliferative diabetic retinopathy (PDR) is an eye disease caused by diabetes. Because this
disease may lead to blindness, effective treatments are urgently needed. However, the …

Correlation of electroretinography b-wave absolute latency, plasma levels of human basic fibroblast growth factor, vascular endothelial growth factor, soluble fatty acid …

FA Zakareia, AA Alderees, KA Al Regaiy… - Journal of Diabetes and …, 2010 - Elsevier
BACKGROUND: We investigated the b-wave latency of electroretinogram (ERG), human
basic fibroblast growth factor (b-FGF), vascular endothelial growth factor (VEGF), soluble …