Reaching an evidence-based prognosis for personalized treatment of multiple sclerosis

D Rotstein, X Montalban - Nature Reviews Neurology, 2019 - nature.com
Personalized treatment is ideal for multiple sclerosis (MS) owing to the heterogeneity of
clinical features, but current knowledge gaps, including validation of biomarkers and …

Impact of sex hormones on immune function and multiple sclerosis development

MC Ysrraelit, J Correale - Immunology, 2019 - Wiley Online Library
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system
(CNS) affecting young people and leading to demyelination and neurodegeneration. The …

Sex and gender issues in multiple sclerosis

HF Harbo, R Gold, M Tintoré - Therapeutic advances in …, 2013 - journals.sagepub.com
Multiple sclerosis (MS) is universally found to be more prevalent in women than men. This
has led to extensive studies of differences in the immune system or nervous system between …

Prolactin and autoimmunity

VV Borba, G Zandman-Goddard… - Frontiers in …, 2018 - frontiersin.org
The great asymmetry of autoimmune diseases between genders represents one of the most
enigmatic observations among the mosaic of autoimmunity. Sex hormones are believed to …

Sex-related factors in multiple sclerosis susceptibility and progression

RR Voskuhl, SM Gold - Nature Reviews Neurology, 2012 - nature.com
The pathogenesis of multiple sclerosis (MS) involves complex interactions between genetic
susceptibility and environmental triggers. Clinical observations suggest that the study of sex …

Multiple sclerosis relapses: epidemiology, outcomes and management. A systematic review

T Kalincik - Neuroepidemiology, 2015 - karger.com
Relapses (episodic exacerbations of neurological signs or symptoms) are a defining feature
of relapsing-remitting multiple sclerosis (MS), the most prevalent MS phenotype. While their …

Exclusive breastfeeding and the effect on postpartum multiple sclerosis relapses

K Hellwig, M Rockhoff, S Herbstritt, N Borisow… - JAMA …, 2015 - jamanetwork.com
Importance Women with multiple sclerosis (MS) experience an elevated risk of relapse after
giving birth. The effect of exclusive breastfeeding on postpartum risk of MS relapse is …

Consensus recommendations for the diagnosis and treatment of multiple sclerosis: 2019 revisions to the MENACTRIMS guidelines

B Yamout, M Sahraian, S Bohlega, M Al-Jumah… - Multiple sclerosis and …, 2020 - Elsevier
With evolving diagnostic criteria and the advent of new oral and parenteral therapies for MS,
most current diagnostic and treatment algorithms need revision and updating. The diagnosis …

Relapse occurrence in women with multiple sclerosis during pregnancy in the new treatment era

R Alroughani, MS Alowayesh, SF Ahmed… - Neurology, 2018 - AAN Enterprises
Objective To determine the rate of relapse occurrence during pregnancy and postpartum.
Methods In a cross-sectional study using the national multiple sclerosis (MS) registry …

Pregnancy-related relapses and breastfeeding in a contemporary multiple sclerosis cohort

A Langer-Gould, JB Smith, KB Albers, AH Xiang, J Wu… - Neurology, 2020 - AAN Enterprises
Objective To determine whether women with multiple sclerosis (MS) diagnosed according to
current criteria are at an increased risk of postpartum relapses and to assess whether this …