Articular cartilage defects, caused by trauma, osteoarthritis, or other diseases, always lead to
severe joint pain and joint dysfunction. Without access to progenitor cells and the supply of …

This review outlines the new developments on chitosan-based bioapplications. Over the last
decade, functional biomaterials research has developed new drug delivery systems and …

Chitin is the second most important natural polymer in the world. The main sources exploited
are two marine crustaceans, shrimp and crabs. Our objective is to appraise the state of the …

The past three decades have seen the emergence of an endeavor called tissue engineering
and regenerative medicine in which scientists, engineers, and physicians apply tools from a …

Scaffolds are implants or injects, which are used to deliver cells, drugs, and genes into the
body. Different forms of polymeric scaffolds for cell/drug delivery are available:(1) a typical …

The present paper intends to overview a wide range of natural–origin polymers with special
focus on proteins and polysaccharides (the systems more inspired on the extracellular …

Tissue engineering is an important therapeutic strategy for present and future medicine.
Recently, functional biomaterial researches have been directed towards the development of …

Purpose To compare the clinical and radiologic efficacy of adipose-derived stem cells
(ADSCs) with fibrin glue and microfracture (MFX) versus MFX alone in patients with …

Musculoskeletal disease and injury are highly prevalent conditions that lead to many
surgical procedures. Autologous tissue transfer, allograft transplantation and nontissue …

Alternatives to efficient viral vectors in gene therapy are desired because of their poor safety
profiles. Chitosan is a promising non-viral nucleotide delivery vector because of its …