Studying the complex molecular mechanisms involved in traumatic brain injury (TBI) is
crucial for developing new therapies for TBI. Current treatments for TBI are primarily focused …

Traumatic brain injury (TBI) is an important global health concern that represents a leading
cause of death and disability. It occurs due to direct impact or hit on the head caused by …

MRI-guided pulsed focused ultrasound (pFUS) combined with systemic infusion of
ultrasound contrast agent microbubbles (MB) causes localized blood–brain barrier (BBB) …

Background Previous research has shown that diet is associated with low‐grade systemic
inflammation among adults. However, no study has yet been conducted to explore the …

Traumatic brain injury (TBI) is one of the leading causes of fatality and disability worldwide.
Despite its high prevalence, effective treatment strategies for TBI are limited. Traumatic brain …

Ruscogenin, an important steroid sapogenin derived from Ophiopogon japonicus, has been
shown to inhibit cerebral ischemic injury. However, its potential molecular action on blood …

This review examines the shared immune-inflammatory, oxidative and nitrosative stress
(IO&NS) and metabolic pathways underpinning metabolic syndrome (MetS), bipolar disorder …

Ischemic cerebral infarction represents a significant cause of disability and death worldwide.
Caspase-1 is activated by the NLRP3/ASC pathway and inflammasomes, thus triggering …

In the highlands of Bordj Bou Arreridj in Northeast Algeria, traditional knowledge about
medicinal plants is still put to use, but has been poorly explored by researchers. In view of its …

Abstract P-glycoprotein (P-gp) is expressed on brain microvessel endothelial cells of blood-
brain barrier (BBB) and elevated after cerebral ischemia. In this study, we explored the …