Risk factors for the progression of mild cognitive impairment to dementia

NL Campbell, F Unverzagt… - Clinics in geriatric …, 2013 - geriatric.theclinics.com
As identified in previously published articles, including those published in this issue, the
detection of early cognitive impairment among older adult populations is worthy of …

Plasma amyloid-β as a predictor of dementia and cognitive decline: a systematic review and meta-analysis

A Koyama, OI Okereke, T Yang, D Blacker… - Archives of …, 2012 - jamanetwork.com
Background Preclinical prediction of Alzheimer disease (AD) is important and critical to
effective intervention. Plasma levels of amyloid-β (Aβ) peptides have been a principal focus …

Plasma tau, neurofilament light chain and amyloid-β levels and risk of dementia; a population-based cohort study

F de Wolf, M Ghanbari, S Licher, K McRae-McKee… - Brain, 2020 - academic.oup.com
CSF biomarkers, including total-tau, neurofilament light chain (NfL) and amyloid-β, are
increasingly being used to define and stage Alzheimer's disease. These biomarkers can be …

Identification of preclinical Alzheimer's disease by a profile of pathogenic proteins in neurally derived blood exosomes: a case‐control study

MS Fiandaca, D Kapogiannis… - Alzheimer's & …, 2015 - Wiley Online Library
Abstract Background Proteins pathogenic in Alzheimer's disease (AD) were extracted from
neurally derived blood exosomes and quantified to develop biomarkers for the staging of …

Plasma Aβ42/40 ratio, p‐tau181, GFAP, and NfL across the Alzheimer's disease continuum: a cross‐sectional and longitudinal study in the AIBL cohort

P Chatterjee, S Pedrini, JD Doecke… - Alzheimer's & …, 2023 - Wiley Online Library
Introduction Plasma amyloid beta (Aβ) 1‐42/Aβ1‐40 ratio, phosphorylated‐tau181 (p‐
tau181), glial fibrillary acidic protein (GFAP), and neurofilament light (NfL) are putative blood …

Plasma and cerebrospinal fluid amyloid beta for the diagnosis of Alzheimer's disease dementia and other dementias in people with mild cognitive impairment (MCI)

C Ritchie, N Smailagic, AH Noel‐Storr… - Cochrane Database …, 2014 - cochranelibrary.com
Background According to the latest revised National Institute of Neurological and
Communicative Disorders and Stroke and the Alzheimer's Disease and Related Disorders …

Factors affecting Aβ plasma levels and their utility as biomarkers in ADNI

JB Toledo, H Vanderstichele, M Figurski, PS Aisen… - Acta …, 2011 - Springer
Previous studies of Aβ plasma as a biomarker for Alzheimer's disease (AD) obtained
conflicting results. We here included 715 subjects with baseline Aβ 1-40 and Aβ 1-42 …

Plasma biomarkers for mild cognitive impairment and Alzheimer's disease

F Song, A Poljak, GA Smythe, P Sachdev - Brain research reviews, 2009 - Elsevier
Purpose of review: With the move toward development of disease modifying treatments,
there is a need for more specific diagnosis of early Alzheimer's disease (AD) and mild …

Meta-analysis of plasma amyloid-β levels in Alzheimer's disease

F Song, A Poljak, M Valenzuela… - Journal of …, 2011 - content.iospress.com
Plasma amyloid-β (Aβ) levels have been proposed as biomarkers of Alzheimer's disease
(AD), but studies have produced inconsistent results. We present a meta-analytic review of …

Plasma Aβ42 and total tau predict cognitive decline in amnestic mild cognitive impairment

TB Chen, YJ Lee, SY Lin, JP Chen, CJ Hu, PN Wang… - Scientific reports, 2019 - nature.com
Levels of amyloid-β (Aβ) and tau peptides in brain have been associated with Alzheimer
disease (AD). The current study investigated the abilities of plasma Aβ42 and total-tau (t-tau) …