Machine learning for metabolic engineering: A review

CE Lawson, JM Martí, T Radivojevic… - Metabolic …, 2021 - Elsevier
Abstract Machine learning provides researchers a unique opportunity to make metabolic
engineering more predictable. In this review, we offer an introduction to this discipline in …

Mass spectrometry‐based high‐throughput proteomics and its role in biomedical studies and systems biology

CB Messner, V Demichev, Z Wang, J Hartl… - …, 2023 - Wiley Online Library
There are multiple reasons why the next generation of biological and medical studies
require increasing numbers of samples. Biological systems are dynamic, and the effect of a …

A machine learning Automated Recommendation Tool for synthetic biology

T Radivojević, Z Costello, K Workman… - Nature …, 2020 - nature.com
Synthetic biology allows us to bioengineer cells to synthesize novel valuable molecules
such as renewable biofuels or anticancer drugs. However, traditional synthetic biology …

Functional genetics of human gut commensal Bacteroides thetaiotaomicron reveals metabolic requirements for growth across environments

H Liu, AL Shiver, MN Price, HK Carlson, VV Trotter… - Cell reports, 2021 - cell.com
Harnessing the microbiota for beneficial outcomes is limited by our poor understanding of
the constituent bacteria, as the functions of most of their genes are unknown. Here, we …

Biological research and self-driving labs in deep space supported by artificial intelligence

LM Sanders, RT Scott, JH Yang, AA Qutub… - Nature Machine …, 2023 - nature.com
Abstract Space biology research aims to understand fundamental spaceflight effects on
organisms, develop foundational knowledge to support deep space exploration and …

Growth-coupled selection of synthetic modules to accelerate cell factory development

E Orsi, NJ Claassens, PI Nikel, SN Lindner - Nature communications, 2021 - nature.com
Synthetic biology has brought about a conceptual shift in our ability to redesign microbial
metabolic networks. Combining metabolic pathway-modularization with growth-coupled …

In vitro continuous protein evolution empowered by machine learning and automation

T Yu, AG Boob, N Singh, Y Su, H Zhao - Cell Systems, 2023 - cell.com
Directed evolution has become one of the most successful and powerful tools for protein
engineering. However, the efforts required for designing, constructing, and screening a large …

Omics-driven biotechnology for industrial applications

B Amer, EEK Baidoo - Frontiers in Bioengineering and Biotechnology, 2021 - frontiersin.org
Biomanufacturing is a key component of biotechnology that uses biological systems to
produce bioproducts of commercial relevance, which are of great interest to the energy …

Machine learning and deep learning in synthetic biology: Key architectures, applications, and challenges

MK Goshisht - ACS omega, 2024 - ACS Publications
Machine learning (ML), particularly deep learning (DL), has made rapid and substantial
progress in synthetic biology in recent years. Biotechnological applications of biosystems …

Artificial intelligence for synthetic biology

M Eslami, A Adler, RS Caceres, JG Dunn… - Communications of the …, 2022 - dl.acm.org
Artificial intelligence for synthetic biology Page 1 88 COMMUNICATIONS OF THE ACM | MAY
2022 | VOL. 65 | NO. 5 review articles IMA GE B YW A COMKA BIOLOGY HAS DRAMATICALLY …