[HTML][HTML] Omicron variant (B. 1.1. 529) and its sublineages: What do we know so far amid the emergence of recombinant variants of SARS-CoV-2?

M Dhawan, ARA Saied, S Mitra, FA Alhumaydhi… - Biomedicine & …, 2022 - Elsevier
Since the start of the COVID-19 pandemic, numerous variants of SARS-CoV-2 have been
reported worldwide. The advent of variants of concern (VOCs) raises severe concerns amid …

Severity of the Omicron SARS‐CoV‐2 variant compared with the previous lineages: A systematic review

M Arabi, Y Al‐Najjar, N Mhaimeed… - Journal of Cellular …, 2023 - Wiley Online Library
The Omicron variant was first detected in October 2021, which evolved from the original
SARS‐CoV‐2 strain and was found to possess many mutations. Immune evasion was one of …

Vaccines elicit highly conserved cellular immunity to SARS-CoV-2 Omicron

J Liu, A Chandrashekar, D Sellers, J Barrett… - Nature, 2022 - nature.com
The highly mutated SARS-CoV-2 Omicron (B. 1.1. 529) variant has been shown to evade a
substantial fraction of neutralizing antibody responses elicited by current vaccines that …

Final analysis of efficacy and safety of single-dose Ad26. COV2. S

J Sadoff, G Gray, A Vandebosch… - … England Journal of …, 2022 - Mass Medical Soc
Abstract Background The Ad26. COV2. S vaccine was highly effective against severe–
critical coronavirus disease 2019 (Covid-19), hospitalization, and death in the primary phase …

[HTML][HTML] Assessing vaccine effectiveness against severe COVID-19 disease caused by omicron variant. Report from a meeting of the World Health Organization

DR Feikin, LJ Abu-Raddad, N Andrews, MA Davies… - Vaccine, 2022 - Elsevier
Vaccine effectiveness is lower and wanes faster against infection and symptomatic disease
caused by the omicron variant of SARS-CoV-2 than was observed with previous variants …

Rapid emergence of SARS-CoV-2 Omicron variant is associated with an infection advantage over Delta in vaccinated persons

C Chaguza, A Coppi, R Earnest, D Ferguson… - Med, 2022 - cell.com
Summary Background The SARS-CoV-2 Omicron variant became a global concern due to
its rapid spread and displacement of the dominant Delta variant. We hypothesized that part …

Vaccine protection against the SARS-CoV-2 Omicron variant in macaques

A Chandrashekar, J Yu, K McMahan, C Jacob-Dolan… - Cell, 2022 - cell.com
The rapid spread of the SARS-CoV-2 Omicron (B. 1.1. 529) variant, including in highly
vaccinated populations, has raised important questions about the efficacy of current …

Durability of heterologous and homologous COVID-19 vaccine boosts

CS Tan, YC Ai-ris, J Yu, J Liu… - JAMA network …, 2022 - jamanetwork.com
Importance Antibody responses elicited by current messenger RNA (mRNA) COVID-19
vaccines decline rapidly and require repeated boosting. Objective To evaluate the …

[HTML][HTML] Dealing with a mucosal viral pandemic: lessons from COVID-19 vaccines

V Mouro, A Fischer - Mucosal immunology, 2022 - Elsevier
The development and deployment of vaccines against COVID-19 demonstrated major
successes in providing immunity and preventing severe disease and death. Yet SARS-CoV …

Role of COVID-19 vaccines in SARS-CoV-2 variants

Z Zhou, Y Zhu, M Chu - Frontiers in immunology, 2022 - frontiersin.org
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2), is a threat to the health of the global population. As the result …